Results 141 to 150 of about 77,093 (285)

Bulgeless Evolution And the Rise of Discs (BEARD)

Astronomy & Astrophysics
We study the formation and evolution of bulgeless galaxies within the Milky Way-Andromeda analogue sample of the TNG50 simulation. Through kinematic decomposition with MORDOR, we identified bulgeless galaxies with a bulge-to-disc mass ratio of B/D ≤ 0.08,
Rosas-Guevara Yetli, Méndez-Abreu Jairo, de Lorenzo-Cáceres Adriana, Cardona-Barrero Salvador, Arjona-Gálvez Elena, Chamorro Cazorla Mario, Corsini Enrico Maria, Costantin Luca, Cuomo Virginia, Di Cintio Arianna, Fernandez David, Gasparri Daniele, Marrero-de la Rosa Carlos, Mayya Divakara, Morelli Lorenzo, Muñoz-Tuñón Casiana, Pinna Francesca, Pizzella Alessandro, Román Javier, Rosa Gonzalez Daniel, Sánchez-Janssen Rubén, Vega Olga, Zarattini Stefano   +22 more
doaj   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

The APO-K2 Catalog. II. Accurate Stellar Ages for Red Giant Branch Stars across the Milky Way

The Astronomical Journal
We present stellar age determinations for 4661 red giant branch stars in the APO-K2 catalog, derived using mass estimates from K2 asteroseismology from the K2 Galactic Archaeology Program and elemental abundances from the Apache Point Galactic Evolution ...
Jack T. Warfield, Joel C. Zinn, Jessica Schonhut-Stasik, James W. Johnson, Marc H. Pinsonneault, Jennifer A. Johnson, Dennis Stello, Rachael L. Beaton, Yvonne Elsworth, Rafael A. García, Savita Mathur, Benoît Mosser, Aldo Serenelli, Jamie Tayar   +13 more
doaj   +1 more source

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

A Perspective on the Milky Way Bulge Bar as Seen from the Neutron-capture Elements Cerium and Neodymium with APOGEE

The Astrophysical Journal
This study probes the chemical abundances of the neutron-capture elements cerium and neodymium in the inner Milky Way from an analysis of a sample of ∼2000 stars in the Galactic bulge bar spatially contained within ∣ X _Gal ∣ < 5 kpc, ∣ Y _Gal ∣ < 3.5 ...
J. V. Sales-Silva, K. Cunha, V. V. Smith, S. Daflon, D. Souto, R. Guerço, A. Queiroz, C. Chiappini, C. R. Hayes, T. Masseron, Sten Hasselquist, D. Horta, N. Prantzos, M. Zoccali, C. Allende Prieto, B. Barbuy, R. Beaton, D. Bizyaev, J. G. Fernández-Trincado, P. M. Frinchaboy, J. A. Holtzman, J. A. Johnson, Henrik Jönsson, S. R. Majewski, D. Minniti, D. L. Nidever, R. P. Schiavon, M. Schultheis, J. Sobeck, G. S. Stringfellow, G. Zasowski   +30 more
doaj   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Insights into the Galactic Bulge Chemodynamical Properties from Gaia Data Release 3

The Astrophysical Journal
We explore the chemodynamical properties of the Galaxy in the azimuthal velocity V _ϕ and metallicity [Fe/H] space using red giant stars from Gaia Data Release 3.
Xiaojie Liao, Zhao-Yu Li, Iulia Simion, Juntai Shen, Robert Grand, Francesca Fragkoudi, Federico Marinacci   +6 more
doaj   +1 more source

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source

The Milky Way and the evolution of disk galaxies

, 2002
We present a phenomenological approach to the study of disk galaxy evolution, based on i) a detailed modelling of the Milky Way (used as a prototype disk galaxy) and ii) an extension of the model to other disks through some simple scaling relations, obtained in the framework of Cold Dark matter models.
openaire   +2 more sources