Results 41 to 50 of about 77,216 (325)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Structure and Evolution of the Milky Way Galaxy [PDF]
International Astronomical Union Colloquium, 1989 AbstractThe combination of chemical abundance, kinematic, and age data for stars near the sun provides important information about the early evolution of the Galaxy. We review available data, with some new analysis, to show that the sum of all available information strongly suggests that the extreme population II subdwarf system formed during a period ...
Gerard Gilmore, Rosemary F.G. Wyse
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Observational Constraints of Radial Migration in the Galactic Disk Driven by the Slowing Bar
The Astrophysical Journal LettersRadial migration is an important dynamical effect that has reshaped the Galactic disk, but its origin has yet to be elucidated. In this work, we present evidence that resonant dragging by the corotation of a decelerating bar could be the main driver of ...
HanYuan Zhang +9 more
doaj +1 more source
The Astrophysical Journal, 2023 We investigate the angular momentum of mono-abundance populations (MAPs) of the Milky Way thick disk by using a sample of 26,076 giant stars taken from APOGEE Data Release (DR) 17 and Gaia early DR3.
Guozhen Hu, Zhengyi Shao, Lu Li
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The time evolution of the Milky Way’s oxygen abundance gradient [PDF]
Monthly Notices of the Royal Astronomical Society, 2018 19 pages, 11 figures, MNRAS, in ...
Mollá, M. +7 more
openaire +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys
The Astrophysical Journal Supplement SeriesPhotometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong +17 more
doaj +1 more source
The Astrophysical Journal, 2023 The study of the elusive hot component ( T ≳ 10 ^7 K) of the Milky Way circumgalactic medium (CGM) is a novel topic for understanding Galactic formation and evolution.
Armando Lara-DI +4 more
doaj +1 more source