Results 41 to 50 of about 76,255 (323)
Chemodynamical evolution of the Milky Way disk [PDF]
Astronomy & Astrophysics, 2013 In the first paper of this series, we present a new approach for studying the chemo-dynamical evolution in disk galaxies, which consists of fusing disk chemical evolution models with compatible numerical simulations of galactic disks. This method avoids known star formation and chemical enrichment problems encountered in simulations.
Minchev, I., Chiappini, C., Martig, M.
openaire +3 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
The Astrophysical Journal, 2023 We investigate the angular momentum of mono-abundance populations (MAPs) of the Milky Way thick disk by using a sample of 26,076 giant stars taken from APOGEE Data Release (DR) 17 and Gaia early DR3.
Guozhen Hu, Zhengyi Shao, Lu Li
doaj +1 more source
A confirmed location in the Galactic halo for the high-velocity cloud 'chain A' [PDF]
, 1999 The high-velocity clouds of atomic hydrogen, discovered about 35 years ago, have velocities inconsistent with simple Galactic rotation models that generally fit the stars and gas in the Milky Way disk.
Kalberla, Peter M. W. +4 more
core +4 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Observational Constraints of Radial Migration in the Galactic Disk Driven by the Slowing Bar
The Astrophysical Journal LettersRadial migration is an important dynamical effect that has reshaped the Galactic disk, but its origin has yet to be elucidated. In this work, we present evidence that resonant dragging by the corotation of a decelerating bar could be the main driver of ...
HanYuan Zhang +9 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Figure Rotation of IllustrisTNG Halos
The Astrophysical Journal, 2023 We use the TNG50 and TNG50 dark matter (DM)-only simulations from the IllustrisTNG simulation suite to conduct an updated survey of halo figure rotation in the presence of baryons.
Neil Ash, Monica Valluri
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys
The Astrophysical Journal Supplement SeriesPhotometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong +17 more
doaj +1 more source