Results 41 to 50 of about 7,457 (263)

Detection of a Supervirial Hot Component in the Milky Way Circumgalactic Medium Along Multiple Sight Lines by Using the Stacking Technique

open access: yesThe Astrophysical Journal, 2023
The study of the elusive hot component ( T ≳ 10 ^7 K) of the Milky Way circumgalactic medium (CGM) is a novel topic for understanding Galactic formation and evolution.
Armando Lara-DI   +4 more
doaj   +1 more source

Dynamical evolution of a bulge in an N-body model of the Milky Way [PDF]

open access: yes, 2012
The detailed dynamical structure of the bulge in the Milky Way is currently under debate. Although kinematics of the bulge stars can be well reproduced by a boxy-bulge, the possible existence of a small embedded classical bulge can not be ruled out.
I. Martinez-Valpuesta   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model

open access: yesThe Astrophysical Journal
This work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj   +1 more source

Figure Rotation of IllustrisTNG Halos

open access: yesThe Astrophysical Journal, 2023
We use the TNG50 and TNG50 dark matter (DM)-only simulations from the IllustrisTNG simulation suite to conduct an updated survey of halo figure rotation in the presence of baryons.
Neil Ash, Monica Valluri
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Searching for Milky Way twins: Radial abundance distribution as a strict criterion

open access: yes, 2023
We search for Milky Way-like galaxies among a sample of approximately 500 galaxies. The characteristics we considered of the candidate galaxies are the following: stellar mass M_star, optical radius R_25, rotation velocity V_rot, central oxygen abundance
G., Tautvaisiene   +2 more
core   +2 more sources

An Inward-moving and Asymmetric Velocity Wave Detected in LAMOST-Gaia

open access: yesThe Astrophysical Journal Letters
The phase space, as coded by kinematic parameters and chemical abundances, is crucial for understanding the formation of the Galactic disk. Using red giant stars from the Galactic thin disk with [Fe/H] > − 0.8 and low- α ratios identified in LAMOST-Gaia,
Yuqin Chen   +5 more
doaj   +1 more source

A Component of the Smith High-velocity Cloud Now Crossing the Galactic Plane

open access: yesThe Astrophysical Journal, 2023
We have identified a new structure in the Milky Way: a leading component of the Smith high-velocity cloud that is now crossing the Galactic plane near longitude 25°. Using new 21 cm H i data from the Green Bank Telescope (GBT), we measured the properties
Felix J. Lockman   +3 more
doaj   +1 more source

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