Results 41 to 50 of about 8,049,523 (305)
, 2012 We briefly describe TRILEGAL, a TRIdimensional modeL of thE GALaxy, and its more recent developments. Particularly relevant is the recent inclusion of a kinematical module to the code, and the present efforts to provide a more solid calibration of Milky ...
Barbieri, Mauro +8 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys
The Astrophysical Journal Supplement SeriesPhotometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong +17 more
doaj +1 more source
Stellar Bars in Isolated Gas-rich Spiral Galaxies Do Not Slow Down
The Astrophysical Journal, 2023 Elongated bar-like features are ubiquitous in galaxies, occurring at the centers of approximately two-thirds of spiral disks in the nearby Universe. Due to gravitational interactions between the bar and the other components of galaxies, it is expected ...
Angus Beane +8 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Additional Evidence for the Existence of a Primordial Disk System
The Astrophysical JournalThe origin of very metal-poor (VMP; [Fe/H] ≤ −2.0) stars on planar orbits has been the subject of great attention since their first discovery. However, prior to the release of the Gaia BP/RP (XP) spectra and large photometric samples such as SkyMapper ...
Shuai Xu +9 more
doaj +1 more source
Structure and Evolution of the Milky Way [PDF]
, 2011 Proc. of the workshop "Red Giants as Probes of the Structure and Evolution of the Milky Way" (Roma, 15-17 Nov 2010), Astrophysics and Space Science Proceedings, ISBN 978-3-642-18417-8 (eds. A. Miglio, J. Montalban, A. Noels).
openaire +2 more sources
Structure and Evolution of the Milky Way Galaxy [PDF]
International Astronomical Union Colloquium, 1989 AbstractThe combination of chemical abundance, kinematic, and age data for stars near the sun provides important information about the early evolution of the Galaxy. We review available data, with some new analysis, to show that the sum of all available information strongly suggests that the extreme population II subdwarf system formed during a period ...
Gerard Gilmore, Rosemary F.G. Wyse
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The population of Planetary Nebulae in the Milky Way
, 2009 Extensive surveys of the Milky Way have provided a global view of the population of planetary nebulae in the Milky Way. Their chemical, dynamical, and morphological properties, the link with their red giant progenitors and white dwarf descendants, and ...
Romano L. M. Corradi
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The Dynamical Evolution of Accreted Star Clusters in the Milky Way [PDF]
, 2016 We perform N-body simulations of star clusters in time-dependant galactic potentials. Since the Milky Way was built up through mergers with dwarf galaxies, its globular cluster population is made up of clusters formed both during the initial collapse of ...
Miholics, Meghan
core +1 more source