Results 191 to 200 of about 30,715 (290)

Discovery of a high-velocity cloud of the Milky Way as a potential dark galaxy. [PDF]

open access: yesSci Adv
Liu XL   +8 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen   +8 more
wiley   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

A binary-related origin mediated by environmental conditions for blue straggler stars. [PDF]

open access: yesNat Commun
Ferraro FR   +9 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

open access: yesAdvanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao   +19 more
wiley   +1 more source

Overview of the ESCAPE Dark Matter Test Science Project for astronomers. [PDF]

open access: yesOpen Res Eur
Pearson J   +3 more
europepmc   +1 more source

A supra-massive population of stellar-mass black holes in the globular cluster Palomar 5. [PDF]

open access: yesNat Astron, 2021
Gieles M   +4 more
europepmc   +1 more source

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