Results 201 to 210 of about 700 (297)

A supra-massive population of stellar-mass black holes in the globular cluster Palomar 5. [PDF]

Nat Astron, 2021
Gieles M, Erkal D, Antonini F, Balbinot E, Peñarrubia J.   +4 more
europepmc   +1 more source

Statistical properties of substructures around Milky Way-sized haloes and their implications for the formation of stellar streams [PDF]

, 2019
Yu Morinaga, Tomoaki Ishiyama, Takanobu Kirihara, Kazuki Kinjo   +3 more
openalex   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Comparison of a new type of Dark Matter with the Milky Way and M31 grand rotation curves. [PDF]

Sci Rep
Law BM.
europepmc   +1 more source

Entropy of the Universe and Hierarchical Dark Matter. [PDF]

Entropy (Basel), 2022
Frampton PH.
europepmc   +1 more source

LMC Calls, Milky Way Halo Answers: Disentangling the Effects of the MW–LMC Interaction on Stellar Stream Populations

Richard A. N. Brooks, Nicolás Garavito-Camargo, Kathryn V. Johnston, Adrian M. Price-Whelan, Jason L. Sanders, Sophia Lilleengen   +5 more
openalex   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

A nearby dark molecular cloud in the Local Bubble revealed via H₂ fluorescence. [PDF]

Nat Astron
Burkhart B, Dharmawardena TE, Bialy S, Haworth TJ, Cruz Aguirre F, Jo YS, Andersson BG, Chung H, Edelstein J, Grenier I, Hamden ET, Han W, Hoadley K, Lee MY, Min KW, Müller T, Pattle K, Peek JEG, Pleiss G, Schiminovich D, Seon KI, Wilson AG, Zucker C.   +22 more
europepmc   +1 more source

The environments of the radio galaxy population in simba. [PDF]

Mon Not R Astron Soc, 2022
Thomas N, Davé R.
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source