Results 81 to 90 of about 29,619 (304)

The Age of the Milky Way Inner Halo

open access: yes, 2012
The Milky Way galaxy is observed to have multiple components with distinct properties, such as the bulge, disk, and halo. Unraveling the assembly history of these populations provides a powerful test to the theory of galaxy formation and evolution, but ...
A Dotter   +28 more
core   +1 more source

Probing the shape and history of the Milky Way halo with orbital spectral analysis [PDF]

open access: yes, 2011
Accurate phase-space coordinates (three components of position and velocity) of individual stars are rapidly becoming available with current and future resolved star surveys.
Debattista, Victor P   +4 more
core   +3 more sources

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

open access: yesAdvanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang   +13 more
wiley   +1 more source

Stellar halos in Illustris: probing the histories of Milky Way-mass galaxies [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2018
13 pages, 12 ...
Lydia M Elias   +6 more
openaire   +3 more sources

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

Characterizing the Chemistry of the Milky Way Stellar Halo: Detailed Chemical Analysis of a Metal-Poor Stellar Stream [PDF]

open access: yes, 2010
We present the results of a detailed abundance analysis of one of the confirmed building blocks of the Milky Way stellar halo, a kinematically-coherent metal-poor stellar stream. We have obtained high resolution and high S/N spectra of 12 probable stream
Aoki   +108 more
core   +2 more sources

Galactic-Seismology Substructures and Streams Hunter with LAMOST and Gaia. I. Methodology and Local Halo Results

open access: yesThe Astrophysical Journal
We present a novel, deep-learning-based method—dubbed Galactic-Seismology Substructures and Streams Hunter, or GS ^3 Hunter for short—to search for substructures and streams in stellar kinematics data.
Guan-Yu Wang   +6 more
doaj   +1 more source

Structure, Kinematics, and Observability of the Large Magellanic Cloud’s Dynamical Friction Wake in Cold versus Fuzzy Dark Matter

open access: yesThe Astrophysical Journal, 2023
The Large Magellanic Cloud (LMC) will induce a dynamical friction (DF) wake on infall to the Milky Way (MW). The MW’s stellar halo will respond to the gravity of the LMC and the dark matter (DM) wake, forming a stellar counterpart to the DM wake.
Hayden R. Foote   +9 more
doaj   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

open access: yesAdvanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen   +13 more
wiley   +1 more source

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