Results 61 to 70 of about 589 (260)

Group accretion in Milky Way-like stellar haloes

open access: yesAstronomy & Astrophysics
As galaxies form hierarchically, larger satellites can accrete alongside smaller companions in group infall events. This coordinated accretion is likely to have left signatures in the Milky Way's stellar halo that we can see today. Our goal is to characterise the possible groups of companions that accompanied larger known accretion events of our Galaxy,
Callingham, Thomas M., Helmi, Amina
openaire   +3 more sources

ON THE SHOULDERS OF GIANTS: PROPERTIES OF THE STELLAR HALO AND THE MILKY WAY MASS DISTRIBUTION [PDF]

open access: yesThe Astrophysical Journal, 2014
Halo stars orbit within the potential of the Milky Way and hence their kinematics can be used to understand the underlying mass distribution. However, the inferred mass distribution depends sensitively upon assumptions made on the density and the velocity anisotropy profiles of the tracers. Also, there is a degeneracy between the parameters of the halo
Prajwal Raj Kafle   +3 more
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Metallicity and α-abundance for 48 Million Stars in Low-extinction Regions in the Milky Way

open access: yesThe Astrophysical Journal
We estimate ([M/H], [ α /M]) for 48 million giants and dwarfs in low-dust extinction regions from the Gaia DR3 XP spectra by using tree-based machine learning models trained on APOGEE DR17 and a metal-poor star sample from Li et al.
Kohei Hattori
doaj   +1 more source

The R-Process Alliance: Chemodynamically Tagged Groups. II. An Extended Sample of Halo r-process-enhanced Stars

open access: yesThe Astrophysical Journal, 2023
Orbital characteristics based on Gaia Early Data Release 3 astrometric parameters are analyzed for ∼1700 r -process-enhanced (RPE; [Eu/Fe] > +0.3) metal-poor stars ([Fe/H] ≤ −0.8) compiled from the R -Process Alliance, the GALactic Archaeology with ...
Derek Shank   +10 more
doaj   +1 more source

Constraining the Milky Way halo potential with the GD-1 stellar stream [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2019
Abstract We use ESA/Gaia astrometry together with SEGUE and LAMOST measurements of the GD-1 stellar stream to explore the improvement on the Galactic gravitational potential that these new data provide. Assuming a realistic universal model for the dark matter halo together with reasonable models of the baryonic components, we find that ...
Malhan, Khyati, Ibata, Rodrigo
openaire   +2 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The Rapid Formation of the Metal-poor Milky Way

open access: yesThe Astrophysical Journal
Our understanding of the assembly timeline of the Milky Way has been transforming along with the dramatic increase in astrometric and spectroscopic data available over the past several years.
Rebecca Woody   +8 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

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