Results 51 to 60 of about 5,772,490 (206)

An old, metal-rich accreted stellar component in the Milky Way stellar disk

, 2022
We study the possibility that the Milky Ways' cool stellar disk includes mergers with ancient stars. Galaxies are understood to form in a hierarchical manner, where smaller (proto-)galaxies merge into larger ones.
Diane K. Feuillet, Sofia Feltzing, Bensby, Thomas, Sahlholdt, Christian, Feuillet, Diane, Feltzing, Sofia,, Feuillet, Diane K., Feltzing, Sofia, Christian Sahlholdt, Thomas Bensby, Bensby, Thomas,   +10 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Metallicity and α-abundance for 48 Million Stars in Low-extinction Regions in the Milky Way

The Astrophysical Journal
We estimate ([M/H], [ α /M]) for 48 million giants and dwarfs in low-dust extinction regions from the Gaia DR3 XP spectra by using tree-based machine learning models trained on APOGEE DR17 and a metal-poor star sample from Li et al.
Kohei Hattori
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Rapid Formation of the Metal-poor Milky Way

The Astrophysical Journal
Our understanding of the assembly timeline of the Milky Way has been transforming along with the dramatic increase in astrometric and spectroscopic data available over the past several years.
Rebecca Woody, Charlie Conroy, Phillip Cargile, Ana Bonaca, Vedant Chandra, Jiwon Jesse Han, Benjamin D. Johnson, Rohan P. Naidu, Yuan-Sen Ting   +8 more
doaj   +1 more source

The R-Process Alliance: Chemodynamically Tagged Groups. II. An Extended Sample of Halo r-process-enhanced Stars

The Astrophysical Journal, 2023
Orbital characteristics based on Gaia Early Data Release 3 astrometric parameters are analyzed for ∼1700 r -process-enhanced (RPE; [Eu/Fe] > +0.3) metal-poor stars ([Fe/H] ≤ −0.8) compiled from the R -Process Alliance, the GALactic Archaeology with ...
Derek Shank, Timothy C. Beers, Vinicius M. Placco, Dmitrii Gudin, Thomas Catapano, Erika M. Holmbeck, Rana Ezzeddine, Ian U. Roederer, Charli M. Sakari, Anna Frebel, Terese T. Hansen   +10 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The progenitors of the Milky Way stellar halo: big bricks favoured over little bricks [PDF]

, 2015
We present a census of blue horizontal branch (BHB) and blue straggler (BS) stars belonging to dwarf galaxies and globular clusters, and compare these counts to that of the Milky Way stellar halo.
Deason, A.J., Weisz, D.R., Belokurov, V.
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dynamics of stellar and HI streams in the Milky Way halo

, 2012
Stellar streams are key players in many aspects of Milky Way studies and, in particular, studying their orbital dynamics is crucial for furthering our understanding of the Milky Wayʼs gravitational potential.
S. Jin, Jin S.
core   +1 more source