Results 51 to 60 of about 30,917 (286)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The PAndAS Field of Streams: stellar structures in the Milky Way halo toward Andromeda and Triangulum

, 2014
We reveal the highly structured nature of the Milky Way stellar halo within the footprint of the PAndAS photometric survey from blue main sequence and main sequence turn-off stars.
Babul, Arif, Bate, Nicholas F., Chapman, Scott C., Collins, Michelle L. M., Conn, Anthony R., Crnojević, Denija, Fardal, Mark A., Ferguson, Annette M. N., Ibata, Rodrigo A., Irwin, Michael J., Lewis, Geraint F., Mackey, A. Dougal, Martin, Nicolas F., McConnachie, Alan W., Navarro, Julio F., Peñarrubia, Jorge, Rich, R. Michael, Tanvir, Nial T., Valls-Gabaud, David   +18 more
core   +3 more sources

Discovery of a New Stellar Subpopulation Residing in the (Inner) Stellar Halo of the Milky Way [PDF]

The Astrophysical Journal Letters, 2019
Abstract We report the discovery of a unique collection of metal-poor giant stars that exhibit anomalously high levels of 28Si, clearly above typical Galactic levels. Our sample spans a narrow range of metallicities, peaking at −1.07 ± 0.06, and exhibits abundance ratios of [Si, Al/Fe] that are as extreme as those observed in Galactic ...
Fernández-Trincado, José, Beers, Timothy, Placco, Vinicius, Moreno, Edmundo, Alves-Brito, Alan, Minniti, Dante, Tang, Baitian, Pérez-Villegas, Angeles, Reylé, Céline, Robin, Annie, Villanova, Sandro   +10 more
openaire   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Deciphering the Kinematic Substructure of Local Dark Matter with LAMOST K Giants

The Astrophysical Journal
Numerical simulations indicate that correlations exist between the velocity distributions of stars and dark matter (DM). We study the local DM velocity distribution based on these correlations.
Hai Zhu, Rui Guo, Juntai Shen, Jianglai Liu, Chao Liu, Xiang-Xiang Xue, Lan Zhang, Shude Mao   +7 more
doaj   +1 more source

The Age of the Milky Way Inner Halo

, 2012
The Milky Way galaxy is observed to have multiple components with distinct properties, such as the bulge, disk, and halo. Unraveling the assembly history of these populations provides a powerful test to the theory of galaxy formation and evolution, but ...
A Dotter, A Dotter, A Dotter, A Renzini, A Sarajedini, A Zolotov, AS Font, B Paczyński, BR Oppenheimer, D Carollo, DR Soderblom, E Gates, E-M Pauli, G Wegner, Jason S. Kalirai, JS Kalirai, JS Kalirai, JS Kalirai, JS Kalirai, LR Bedin, M Kilic, P Bergeron, P Jofré, P-E Tremblay, P-E Tremblay, R Napiwotzki, S Moehler, SL Shapiro, TC Beers   +28 more
core   +1 more source

Low-metallicity stellar halo populations as tracers of dark matter haloes [PDF]

, 2014
We analyse the density profiles of the stellar halo populations in eight Milky-Way mass galaxies, simulated within the $\Lambda$-Cold Dark Matter scenario.
Scannapieco, Cecilia, Tissera, Patricia B.   +1 more
core   +2 more sources

The stability of stellar discs in Milky Way-sized dark matter haloes [PDF]

Monthly Notices of the Royal Astronomical Society, 2015
22 pages, 23 figures, 1 tables. Accepted for publication in MNRAS.
Denis Yurin, Volker Springel
openaire   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

A Catalog of Distance Determinations for 5 Million Stars in LAMOST DR10

The Astronomical Journal
Using the distance estimation method outlined in J. L. Carlin et al., a Bayesian approach specifically tailored for LAMOST data, we estimated distances for 7,450,303 spectra from 5,394,174 unique stars in the LAMOST DR10 low-resolution data set.
Chengqun Yang, Xiang-Xiang Xue, Chao Liu, Hao Tian, Ling Zhu, Lan Zhang   +5 more
doaj   +1 more source