Results 41 to 50 of about 30,917 (286)

Are dSph galaxies Galactic building blocks?

open access: yesEPJ Web of Conferences, 2012
Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure
Gilmore G., Asiri H.M.
doaj   +1 more source

Insight Into the Formation of the Milky Way Through Cold Halo Substructure. I. The ECHOS of Milky Way Formation [PDF]

open access: yes, 2009
We identify ten -- seven for the first time -- elements of cold halo substructure (ECHOS) in the volume within 17.5 kpc of the Sun in the inner halo of the Milky Way.
Abadi   +98 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Dichotomy of the Halo of the Milky Way

open access: yes, 2008
We summarize evidence that the halo of the Milky Way comprises two different, and broadly overlapping, stellar components. The two structures exhibit different chemical compositions, spatial distributions, and kinematics.
Akira Ohnishi   +8 more
core   +1 more source

Characterizing the Chemistry of the Milky Way Stellar Halo: Detailed Chemical Analysis of a Metal-Poor Stellar Stream [PDF]

open access: yes, 2010
We present the results of a detailed abundance analysis of one of the confirmed building blocks of the Milky Way stellar halo, a kinematically-coherent metal-poor stellar stream. We have obtained high resolution and high S/N spectra of 12 probable stream
Aoki   +108 more
core   +2 more sources

On the Corotation of Milky Way Satellites: LMC-mass Satellites Induce Apparent Motions in Outer Halo Tracers

open access: yesThe Astrophysical Journal
Understanding the physical mechanism behind the formation of a corotating thin plane of satellite galaxies, like the one observed around the Milky Way (MW), has been challenging.
Nicolás Garavito-Camargo   +10 more
doaj   +1 more source

Assembly of the outer Galactic stellar halo in the hierarchical model

open access: yes, 2010
We provide a set of numerical N-body simulations for studying the formation of the outer Milky Ways's stellar halo through accretion events. After simulating minor mergers of prograde and retrograde orbiting satellite halo with a Dark Matter main halo ...
Adelman-McCarthy   +15 more
core   +1 more source

A mass-dependent density profile for dark matter haloes including the influence of galaxy formation [PDF]

open access: yes, 2014
We introduce a mass-dependent density profile to describe the distribution of dark matter within galaxies, which takes into account the stellar-to-halo mass dependence of the response of dark matter to baryonic processes.
Aaron A. Dutton   +86 more
core   +2 more sources

The Milky Way's stellar halo - lumpy or triaxial?

open access: yesJournal of Physics: Conference Series, 2006
10 pages, 10 figs, to appear in proceedings of conference "Physics at the end of the Galactic Cosmic Ray Spectrum", Journal of Physics: Conf. series, eds. G.
Newberg, Heidi Jo, Yanny, Brian
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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