Results 41 to 50 of about 30,917 (286)
Are dSph galaxies Galactic building blocks?
EPJ Web of Conferences, 2012 Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure Gilmore G., Asiri H.M.doaj +1 more sourceInsight Into the Formation of the Milky Way Through Cold Halo
Substructure. I. The ECHOS of Milky Way Formation [PDF]
, 2009 We identify ten -- seven for the first time -- elements of cold halo
substructure (ECHOS) in the volume within 17.5 kpc of the Sun in the inner halo
of the Milky Way.Abadi, Abadi, Abazajian, Allende Prieto, Allende Prieto, An, Audrey Simmons, Bell, Belokurov, Belokurov, Binney, Bovy, Brian Yanny, Bullock, Carlos Allende Prieto, Carretta, Chen, Chiba, Chiba, Clem, Constance M. Rockosi, Dan Oravetz, Diemand, Dmitry Bizyaev, Duffau, Elena Malanushenko, Fellhauer, Font, Gilmore, Gilmore, Gould, Grillmair, Grillmair, Grillmair, Grillmair, Gunn, Gunn, Harding, Helmi, Helmi, Hogg, Howard, Howard Brewington, Ibata, Ivezić, Ivezić, Johnston, Johnston, Johnston, Jurić, Kaike Pan, Kepley, Kevin C. Schlaufman, Kirby, Klement, Klement, Law, Lee, Lee, Lindegren, Majewski, Martínez-Delgado, Monet, Morrison, Morrison, Munn, Newberg, Nissen, Odenkirchen, Padmanabhan, Peñarrubia, Pier, Robertson, Rocha-Pinto, Rockosi, Sirko, Sirko, Smith, Smith, Sommer-Larsen, Starkenburg, Steinmetz, Stephanie Snedden, Stewart, Timothy C. Beers, Viktor Malanushenko, Vivas, Vivas, Watkins, White, Willett, Xue, Yanny, Yanny, Yanny, York, Young Sun Lee, Zolotov, Zwitter +98 morecore +2 more sourcesIMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd +9 morewiley +1 more sourceThe Dichotomy of the Halo of the Milky Way
, 2008 We summarize evidence that the halo of the Milky Way comprises two different,
and broadly overlapping, stellar components. The two structures exhibit
different chemical compositions, spatial distributions, and kinematics.Akira Ohnishi, Daniela Carollo, Kiyoshi Kato, Masayuki Y. Fujimoto, Shigeru Kubono, Takaya Nozawa, Takuma Suda, Timothy C. Beers, Toshitaka Kajino +8 morecore +1 more sourceCharacterizing the Chemistry of the Milky Way Stellar Halo: Detailed
Chemical Analysis of a Metal-Poor Stellar Stream [PDF]
, 2010 We present the results of a detailed abundance analysis of one of the
confirmed building blocks of the Milky Way stellar halo, a
kinematically-coherent metal-poor stellar stream. We have obtained high
resolution and high S/N spectra of 12 probable stream Aoki, Arlandini, Beers, Bell, Belokurov, Belokurov, Belokurov, Biémont, Biémont, Biémont, Blackwell, Blackwell, Blackwell, Booth, Brown, Carlin, Carney, Carney, Castelli, Chiba, Chou, Chou, Christopher Sneden, Cohen, Cohen, Cohen, Cohen, Da Costa, Demarque, Den Hartog, Den Hartog, Farouqi, Frebel, Frebel, Frebel, Fuhr, Fulbright, Gallino, Geha, George W. Preston, Grevesse, Griffin, Grillmair, Grillmair, Grillmair, Han, Hannaford, Honda, Ian B. Thompson, Ian U. Roederer, Ivans, Ivarsson, Keeping, Kepley, Kirby, Klement, Kratz, Kurucz, Lai, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lee, Li, Lynden Bell, Majewski, Martinson, Martínez-Delgado, Milone, Morrison, Nahar, Newberg, Newberg, Nitz, Norris, Odenkirchen, Pickering, Pickering, Piotto, Preston, Roederer, Roederer, Roederer, Sadakane, Schatz, Shetrone, Skrutskie, Smith, Sneden, Sneden, Sneden, Sneden, Sobeck, Spite, Starkenburg, Stephen A. Shectman, Takeda, Vivas, Wallerstein, Whaling, Yanny, York, Zhang, Zucker +108 morecore +2 more sourcesOn the Corotation of Milky Way Satellites: LMC-mass Satellites Induce Apparent Motions in Outer Halo Tracers
The Astrophysical JournalUnderstanding the physical mechanism behind the formation of a corotating thin plane of satellite galaxies, like the one observed around the Milky Way (MW), has been challenging.Nicolás Garavito-Camargo, Adrian M. Price-Whelan, Jenna Samuel, Emily C. Cunningham, Ekta Patel, Andrew Wetzel, Kathryn V. Johnston, Arpit Arora, Robyn E. Sanderson, Lehman Garrison, Danny Horta +10 moredoaj +1 more sourceAssembly of the outer Galactic stellar halo in the hierarchical model
, 2010 We provide a set of numerical N-body simulations for studying the formation
of the outer Milky Ways's stellar halo through accretion events. After
simulating minor mergers of prograde and retrograde orbiting satellite halo
with a Dark Matter main halo ...Adelman-McCarthy, Belokurov, Binney, Boylan-Kolchin, Bullock, Chiba, Curir, Grillmair, Huang, Miceli, Moore, Navarro, Press, White, Yanny, Zolotov +15 morecore +1 more sourceA mass-dependent density profile for dark matter haloes including the influence of galaxy formation [PDF]
, 2014 We introduce a mass-dependent density profile to describe the distribution of dark matter within galaxies, which takes into account the stellar-to-halo mass dependence of the response of dark matter to baryonic processes.Aaron A. Dutton, Agertz, Alexander Knebe, Andrea V. Macciò, Arianna Di Cintio, Battaglia, Blumenthal, Brook, Brook, Brook, Bullock, Catena, Chabrier, Chris B. Brook, Cole, de Blok, de Blok, Deason, Del Popolo, Del Popolo, Di Cintio, Di Cintio, Duffy, Dutton, Dutton, Dutton, Dutton, El-Zant, Freyer, Gao, Gill, Gnedin, Goerdt, Goerdt, Governato, Governato, Greg S. Stinson, Guo, Hernquist, Jaffe, Kannan, Kannan, Katz, Kay, Kennicutt, Knollmann, Kuzio de Naray, Kuzio de Naray, Macciò, Macciò, Macciò, Martizzi, Mashchenko, Merritt, Mo, Moore, Moster, Muñoz-Cuartas, Navarro, Navarro, Navarro, Navarro, Nesti, Obreja, Oh, Peñarrubia, Pontzen, Pontzen, Power, Prada, Read, Read, Romano-Díaz, Salucci, Schmidt, Shen, Simon, Spergel, Springel, Stinson, Stinson, Stinson, Teyssier, Tonini, Wadsley, Walker, Zolotov +86 morecore +2 more sourcesKeratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer +13 morewiley +1 more source