Results 81 to 90 of about 30,917 (286)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

Elemental Abundances in M31: Alpha and Iron Element Abundances from Low-Resolution Resolved Stellar Spectroscopy in the Stellar Halo [PDF]

open access: yes, 2019
Measurements of [Fe/H] and [$\alpha$/Fe] can probe the minor merging history of a galaxy, providing a direct way to test the hierarchical assembly paradigm.
Cunningham, Emily C.   +4 more
core   +3 more sources

The Rapid Formation of the Metal-poor Milky Way

open access: yesThe Astrophysical Journal
Our understanding of the assembly timeline of the Milky Way has been transforming along with the dramatic increase in astrometric and spectroscopic data available over the past several years.
Turner Woody   +8 more
doaj   +1 more source

The puzzling assembly of the Milky Way halo – contributions from dwarf Spheroidals and globular clusters

open access: yesEPJ Web of Conferences, 2012
While recent sky surveys have uncovered large numbers of ever fainter Milky Way satellites, their classification as star clusters, low-luminosity galaxies, or tidal overdensities remains often unclear. Likewise, their contributions to the build-up of the
Lépine S., Koch A., Çalışkan Ş.
doaj   +1 more source

The masses and metallicities of stellar haloes reflect galactic merger histories

open access: yes, 2017
There is increasing observational and theoretical evidence for a correlation between the metallicity and the mass of the stellar halo for galaxies with Milky Way-like stellar masses.
Bell, Eric, D'Souza, Richard
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni   +13 more
wiley   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

open access: yesAdvanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang   +6 more
wiley   +1 more source

Chemical fingerprinting of stellar populations in the Milky Way halo [PDF]

open access: yesProceedings of the International Astronomical Union, 2012
AbstractThe idea of “chemically fingerprinting“ stars to their birth systems has been discussed over the last decade. Here we present an investigation of the chemical abundance patterns of halo substructures using high-resolution spectra. In particular, we study the abundances of the α-like element titanium (Ti) and the s-process elements yttrium (Y ...
openaire   +1 more source

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

open access: yesAdvanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk   +7 more
wiley   +1 more source

Generalized Rotation Curves of the Milky Way from the GAIA DR3 Data Set: Constraints on Mass Models

open access: yesThe Astrophysical Journal
The circular velocity curve traced by stars provides a direct means of investigating the potential and mass distribution of the Milky Way. Recent measurements of the Galaxy’s rotation curve have revealed a significant decrease in velocity for Galactic ...
Francesco Sylos Labini
doaj   +1 more source

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