Results 81 to 90 of about 13,860 (288)
Using frequency maps to explore the distribution function of the Milky Way stellar halo
Resolved surveys of the Milky Way's stellar halo can obtain all 6 phase space coordinates of tens of thousands of individual stars, making it possible to compute their 3-dimensional orbits.
Valluri M.
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Constraining the Milky Way halo potential with the GD-1 stellar stream [PDF]
Abstract We use ESA/Gaia astrometry together with SEGUE and LAMOST measurements of the GD-1 stellar stream to explore the improvement on the Galactic gravitational potential that these new data provide. Assuming a realistic universal model for the dark matter halo together with reasonable models of the baryonic components, we find that ...
Malhan, Khyati, Ibata, Rodrigo
openaire +2 more sources
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
We present a novel, deep-learning-based method—dubbed Galactic-Seismology Substructures and Streams Hunter, or GS ^3 Hunter for short—to search for substructures and streams in stellar kinematics data.
Guan-Yu Wang +6 more
doaj +1 more source
Diverse stellar haloes in nearby Milky Way mass disc galaxies [PDF]
26 pages, 17 figures.
Harmsen, B. +6 more
openaire +4 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Precise Asteroseismic Ages for the Helmi Streams
The Helmi streams are remnants of a dwarf galaxy that was accreted by the Milky Way and whose stars now form a distinct kinematic and chemical substructure in the Galactic halo. Precisely age-dating these typically faint stars of extragalactic origin has
Christopher J. Lindsay +8 more
doaj +1 more source
Orbital characteristics based on Gaia Early Data Release 3 astrometric parameters are analyzed for ∼1700 r -process-enhanced (RPE; [Eu/Fe] > +0.3) metal-poor stars ([Fe/H] ≤ −0.8) compiled from the R -Process Alliance, the GALactic Archaeology with ...
Derek Shank +10 more
doaj +1 more source
Group accretion in Milky Way-like stellar haloes
As galaxies form hierarchically, larger satellites can accrete alongside smaller companions in group infall events. This coordinated accretion is likely to have left signatures in the Milky Way's stellar halo that we can see today. Our goal is to characterise the possible groups of companions that accompanied larger known accretion events of our Galaxy,
Callingham, Thomas M., Helmi, Amina
openaire +3 more sources

