Results 81 to 90 of about 5,772,490 (206)

A Novel Approach to Identifying Substructures through Analysis of Metallicity Distribution Functions

The Astrophysical Journal
We present a new method for identifying Galactic halo substructures accreted from dwarf galaxies by combining metallicity distribution functions (MDFs) with orbital parameters.
Young Kwang Kim, Young Sun Lee, Timothy C. Beers   +2 more
doaj   +1 more source

Metal Compound‐Based Non‐Enzymatic Electrochemical Cholesterol Sensors: Emerging Materials and Mechanistic Insights

Advanced Materials Interfaces, EarlyView.
This review discusses recent progress in metal complex‐based, non‐enzymatic electrochemical sensors for cholesterol detection. We examine metal oxides, metal sulfides, and hybrid nanomaterials, highlighting their catalytic mechanisms and material design strategies.
Longfei (Jack) Yin, Chao‐Tsen (Rora) Chen, Jacopo Giaretta, Thanh‐Qua Nguyen, Hoang‐Phuong Phan, Fariba Dehghani, Syamak Farajikhah   +6 more
wiley   +1 more source

All-sky Kinematics of the Distant Halo: The Reflex Response to the LMC

The Astrophysical Journal
The infall of the Large Magellanic Cloud (LMC) is predicted to displace the inner Milky Way (MW), imprinting an apparent “reflex motion” on the observed velocities of distant halo stars. We construct the largest all-sky spectroscopic data set of luminous
Vedant Chandra, Rohan P. Naidu, Charlie Conroy, Nicolas Garavito-Camargo, Chervin Laporte, Ana Bonaca, Phillip A. Cargile, Emily Cunningham, Jiwon Jesse Han, Benjamin D. Johnson, Hans-Walter Rix, Yuan-Sen Ting, Rebecca Woody, Dennis Zaritsky   +13 more
doaj   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Predictions for the Detectability of Milky Way Satellite Galaxies and Outer-Halo Star Clusters with the Vera C. Rubin Observatory

The Open Journal of Astrophysics
We predict the sensitivity of the Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) to faint, resolved Milky Way satellite galaxies and outer-halo star clusters.
Kabelo Tsiane, Sidney Mau, Alex Drlica-Wagner, Jeffrey L. Carlin, Peter S. Ferguson, Keith Bechtol, Ethan O. Nadler, Annika H. G. Peter, Yao-Yuan Mao, Adam J. Thornton, LSST Dark Energy Science Collaboration   +10 more
doaj   +1 more source

Formation of Milky Way-type stellar haloes in a Λ-CDM cosmology

EPJ Web of Conferences, 2012
Recent observations suggest that the Milky Way stellar halo has a ‘dual nature’, meaning that both dissipational and dissipationless processes play a role in its build-up.
Font A.S.
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Characterizing the Velocity Anisotropy of the Milky Way’s Stellar Halo

The Astrophysical Journal
Modeling the Milky Way stellar halo requires well-determined density and velocity anisotropy profiles. However, it has been challenging to gather a large sample of stars with six-dimensional data that extend beyond 40 kpc to map the outer halo.
F. O. Barbosa, A. Pérez-Villegas, S. Rossi, R. M. Santucci, L. Aguilar, H. D. Perottoni, G. Limberg, L. Borbolato, J. V. Nogueira-Santos   +8 more
doaj   +1 more source

Quantifying Kinematic Substructure in the Milky Way’s Stellar Halo [PDF]

, 2011
We present and analyze the positions, distances, and radial velocities for over 4000 blue horizontal-branch (BHB) stars in the Milky Way's halo, drawn from SDSS DR8.
Liu, Chao, Kathryn V. Johnston, Bell, Eric F., Johnston, Kathryn V., Morrison, Heather, Benjamin A. Weaver, Xiang-xiang Xue, Koposov, Sergey E, Rix, Hans-Walter, Sergey E. Koposov, Bullock, James S, Young Sun Lee, Weaver, Benjamin A., Yanny, Brian, Luo, Ali, Ali Luo, Lee, Young Sun, Rockosi, Constance, Bullock, James S., Zhao, Gang, Kang, Xi, Johnston, Kathryn V, Weaver, Benjamin A, James S. Bullock, Gang Zhao, Chao Liu, Koposov, Sergey E.; id_orcid, Eric F. Bell, Xi Kang, Xue, Xiang-Xiang, Hans-walter Rix, Heather Morrison, Bell, Eric F, Constance Rockosi, Beers, Timothy C., Brian Yanny, Beers, Timothy C, Timothy C. Beers   +37 more
core   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source