Results 101 to 110 of about 5,772,490 (206)
Figuring Out Gas and Galaxies in Enzo (FOGGIE). VII. The (Dis)assembly of Stellar Halos
Over the next decade, the astronomical community will be commissioning multiple wide-field observatories well suited for studying stellar halos in both integrated light and resolved stars. In preparation for this, we use five high-resolution cosmological
Anna C. Wright +9 more
doaj +1 more source
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong +6 more
wiley +1 more source
Chemical Diversity on Small Scales: Abundance Analysis of the Tucana V Ultrafaint Dwarf Galaxy
The growing number of Milky Way satellites detected in recent years has introduced a new focus for stellar abundance analysis. Abundances of stars in satellites have been used to probe the nature of these systems and their chemical evolution.
Terese T. Hansen +7 more
doaj +1 more source
ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng +9 more
wiley +1 more source
Detection of the Actinide Th in an r-process-enhanced Star with Accretion Origin
The thorium and six second-peak r -process element (56 ≤ Z ≤ 72) abundances are determined for the α -poor star LAMOST J1124+4535 based on a high-resolution spectrum obtained with the High Dispersion Spectrograph on the Subaru Telescope. The age of J1124+
Qianfan Xing +6 more
doaj +1 more source
A disrupting open cluster far into the Milky Way halo: star formation in the Magellanic stream?
We have found a young (~130 Myr), metal-poor ([Fe/H] ~ -1.1) stellar association at a heliocentric distance D ~ 29 kpc, placing it far into the Milky Way halo.
Price-Whelan, Adrian (5364847) +1 more
core +1 more source
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei +10 more
wiley +1 more source
A New Tidal Stream Discovered in Gaia DR3
Thanks to the precise astrometric measurements of proper motions by the Gaia mission, a new tidal stellar stream has been discovered in the northern hemisphere. The distribution of star count shows that the stream is approximately 80° long and 1.°70 wide.
Hao Tian +4 more
doaj +1 more source
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
The Velocity Field of Our Milky Way Outer Stellar Halo Based on DESI DR2
Using 64,000 halo K giants from the Dark Energy Spectroscopic Instrument second Data Release (DR2), we decompose the Milky Way (MW) stellar halo between 3 and 160 kpc into metal-rich (MR) and metal-poor (MP) components via a Gaussian mixture model.
Songting Li +55 more
doaj +1 more source

