Results 91 to 100 of about 125,939 (330)

Construction of an inflammatory microenvironment-responsive HDL-mimetic nanoparticle and evaluation of its in vitro anti-atherosclerotic activity

Di-san junyi daxue xuebao, 2020
Objective To construct an inflammation-responsive high-density lipoprotein (HDL)-mimetic nanoparticle with anti-atherosclerotic activity using a bioinspired strategy based on a oxidation-responsive material.
LIU Renfeng, Department of Pharmaceutics, Faculty of Pharmacy and Laboratary Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, China , DOU Yin, ZHANG Jianxiang   +3 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Reconstruction of mimetic gravity in a non-singular bouncing universe from quantum gravity

, 2019
We illustrate a general reconstruction procedure for mimetic gravity. Focusing on a bouncing cosmological background, we derive general properties that must be satisfied by the function $f(\Box\phi)$ implementing the limiting curvature hypothesis.
de Cesare, Marco
core   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Supplementary Figures 1-6, Tables 1-2, Methods from Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

, 2023
Herman H. Cheung, Douglas J. Mahoney, Eric C. LaCasse, Robert G. Korneluk   +3 more
openalex   +3 more sources

HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL

Lipids in Health and Disease, 2011
Background The role of pro-inflammatory lipids in systemic immune activation in HIV infection remains largely unknown. We hypothesized that HIV-1-infected persons on antiretroviral therapy would have pro-inflammatory high density lipoprotein (HDL), and ...
Navab Kaveh, Currier Judith S, Yang Otto O, Kelesidis Theodoros, Fogelman Alan M, Navab Mohamad   +5 more
doaj   +1 more source

Exploring the Production of Extracellular Matrix by Astrocytes in Response to Mimetic Traumatic Brain Injury [PDF]

, 2016
Following injury to the central nervous system, extracellular modulations are apparent at the site of injury, often resulting in a glial scar. Astrocytes are mechanosensitive cells, which can create a neuroinhibitory extracellular environment in response
Walker, Addison
core   +2 more sources

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

A Stress/Displacement Virtual Element Method for Plane Elasticity Problems

, 2017
The numerical approximation of 2D elasticity problems is considered, in the framework of the small strain theory and in connection with the mixed Hellinger-Reissner variational formulation. A low-order Virtual Element Method (VEM) with a-priori symmetric
Artioli, E., de Miranda, S., Lovadina, C., Patruno, L.   +3 more
core   +1 more source