Results 161 to 170 of about 3,581 (198)

PRECURSORS OF MIMOSINE IN MIMOSA PUDICA

Canadian Journal of Biochemistry, 1965
In Mimosa pudica L. both L- and DL-lysine serve as specific precursors of the -γ-pyridone nucleus of mimosine. Succinic acid is also incorporated into the nucleus. Glycerol and glyceric acid enter the side chain of mimosine. An improved method for the isolation of mimosine from M. pudica is described.
H P, Tiwari, I D, Spenser
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Polarographic investigation of mimosine

Recueil des Travaux Chimiques des Pays-Bas, 1950
AbstractA polarographic investigation of mimosine was made in order to obtain more information on its polar structure. The polarographic behaviour of mimosine is abnormal, but it is possible to give a reaction scheme explaining these phenomena.
Sj. L. Bonting, F. R. Schepman
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A SYNTHESIS OF MIMOSINE

Canadian Journal of Chemistry, 1962
DL-Mimosine has been sinthesized by debenzylation and detosylation of the product obtained by condensation of 3-benzyloxy-4-pyrone with β-amino-α-tosylaminopropionic acid.A new method for the isolation of mimosine from Leucaena glauca Benth. is described.
Ian D. Spenser, Albert D. Notation
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Antidermatophytic and bacterial activity of mimosine

Phytotherapy Research, 2005
Mimosine, a non-protein aromatic amino acid was tested at 100, 50 and 25 microg/mL on some human pathogenic bacteria and fungi. Mimosine exhibited total lethality towards Trichophyton tonsurans and Trichophyton rubrum at 100 microg/mL. Among the tested bacteria Staphylococcus aureus was inhibited to a larger extent than the other bacteria.
R, Anitha, S, Jayavelu, K, Murugesan
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Biosynthesis of mimosine

Phytochemistry, 1964
Abstract Administration of [2-14C]- dl -lysine to Leucaena glauca results in incorporation of radioactivity into mimosine, pipecolic acid and 5-hydroxypipecolic acid. Degradation of the mimosine reveals that 95% of the radioactivity is present in the pyridone ring.
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The absolute configuration of mimosine

Recueil des Travaux Chimiques des Pays-Bas, 1964
AbstractDegradation of the plant amino acid (‐)‐mimosine yielded optically pure (+)‐α,β‐diaminopropionic acid hydrobromide identical with the acid obtained from L‐asparagine. (‐)‐Mimosine therefore belongs to the Ls‐series.
H. C. Beyerman, L. Maat, M. P. Hegarty
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Inhibition of Growth of Hair by Mimosine

Nature, 1962
Loss of hair in animals following ingestion of seeds and foliage of Leucaena glauca was first reported in 18971. Sudden loss of hair in native women has been ascribed to consumption of Leucaena glauca seeds2. The toxic principle contained in this plant is a water-soluble amino-acid termed leucenol, and is identical with mimosine obtained from Mimosa ...
R G, CROUNSE, J D, MAXWELL, H, BLANK
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Effect of mimosine on the rat fetus

Teratology, 1970
AbstractGroups of 16 pregnant rats per treatment were fed ad libitum a basal diet containing 0, 0.3, 0.5, or 0.7% mimosine or allowed a restricted intake of the diet with no mimosine until killed on day 20 of gestation.Incremental increases of mimosine caused significant (P<0.01) decreases in daily feed consumption, weight gain per unit of food, and
S, Dewreede, O, Wayman
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The Dual Effect of Mimosine on DNA Replication

Experimental Cell Research, 1997
The plant amino acid, mimosine, is an extremely effective inhibitor of DNA replication in mammalian cells, but the mechanism by which this inhibition is achieved is unknown. The drug has been proposed either to inhibit initiation at origins of replication or to inhibit chain elongation by lowering nucleotide pool levels.
R F, Kalejta, J L, Hamlin
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Antitumor Activity of Mimosine and Mimosine HYdrochloride against B16 Melanoma in BDF Mice

1976
Mimosine, β-N-(3-hydroxy-4-pyridone) α-aminopropionic acid, and its hydrochloride produced significant inhibition of subcutaneously transplanted murine B16 melanoma in BDF1 female mice. In such mice during mimosine treatment differences developed in the reactivity of both surface membrane and cytoplasmic antigens as compared to untreated cells.
T. A. Khwaja, T. C. Hall, K. M. A. Sheikh   +2 more
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