Results 111 to 120 of about 10,558 (304)
, 2001 The Sullivan Mine has been operated by Cominco Ltd. since 1909, and is scheduled for closure in December of 2001. The Sullivan ore body is acid generating but operated for many decades before the need to control acid rock drainage (ARD) was recognized ...
Tarasoff, Dan, Ramdin, Zoe
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Using decision science to build trust in mine closure decisions
, 2023 In today’s changing social and environmental landscape, society requires organizations to shift to an everevolving world of ‘tell me what you are doing’, through to ‘show me what impact you are having’, and now to ‘involve me in your work’.
Schneider, Daniel +2 more
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REM: International Engineering JournalMine closure is the set of all activities that follow the end of the productive phase of a mine, characterizing itself as the process of returning an area transformed by mining into a new condition of sustainability, considering the potential future and ...
Viviane da Silva Borges Barbosa +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A sustainable legacy : utilizing mine assets post-closure : Island Copper Mine
, 2000 The Island Copper Mine operated by BHP Minerals Canada Ltd., a subsidiary of BHP International of Australia, ceased operations on December 31, 1995 on depletion of the copper-molybdenum orebody on the northern tip of Vancouver Island.
Welchman, Brian, Aspinall, Craig
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2011 The Kemess South mine site is owned and operated by Northgate Minerals Corporation (NMC), and is a large porphyry gold and copper open-pit mine that is scheduled for closure in 2011.
North, Reg +3 more
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Mine Closure 2022: Proceedings of the 15th International Conference on Mine Closure (Volume 1)
, 2022 The economically feasible, environmentally benign and socially acceptable closure of mines is one of the greatest challenges facing the mining industry.
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