Results 71 to 80 of about 6,946 (259)

Criteria for decision-making for the best reclamation solution [PDF]

open access: yesPodzemni Radovi
Mine site reclamation is a relevant step in maintaining ecological balance after mining activities. Although mining activities provide many economic benefits, they often have a negative impact on the environment.
Gaćina Radmila   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Impact of the Closure of Mines on the Local Environment from the Perspective of Qualitative Research on the Example of Poland

open access: yesManagement Systems in Production Engineering
The main aim of the article is to determine the impact of mine closure on the local environment, with particular emphasis on the social, economic and environmental problems that arise when mining activities are limited or discontinued.
Marszowski Ryszard   +1 more
doaj   +1 more source

Environmental and Closure Costs in Strategic Mine Planning, Models, Regulations, and Policies

open access: yesResources
This study explores the evolution of mine planning, with particular emphasis on the integration of environmental and social factors in alignment with the sustainable development.
David Oliveros-Sepúlveda   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Probability of failure of waste disposals sites in Žirovski vrh uranium mine

open access: yesGeologija, 2002
The only Uranium mine in Slovenia @irovski vrh was closed in 1990 due to economic reasons. After the closure extensive decommissioning works in the mine and in the surrounding began.
Tomaž Beguš
doaj  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Reading mine closure through Tłı̨chǫ self-determination

open access: yesJournal of Political Ecology
In Northern Canada, the Tłı̨chǫ have experienced a long history of settler-imposed mining. The history of the mines is written into Tłı̨chǫ place names that hold the knowledge of ecological harm and repair, the community re-purposing of mining equipment ...
John B Zoe   +2 more
doaj   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Dyskurs żalu czy ulgi?

open access: yesPoliteja, 2017
The Discourse of Regret or Relief? Wałbrzych Twenty Years After the Closure of the Mines The paper presents the results of field research carried out in 2015 in Wałbrzych, focused on as well memory as arising postmemory of citizens, clustered around ...
Agata Rejowska‑Pasek, Zbigniew Pasek
doaj   +1 more source

Home - About - Disclaimer - Privacy