Results 81 to 90 of about 10,558 (304)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2015 Many significant advancements have been made in the mine closure process over the past several decades, including “design for closure,” the development of comprehensive mine closure planning and the regulatory requirement for financial assurances for ...
Thorpe, M. B., Flynn, M., Holmes, R.
core
Design of inspection system for coal mine equipments based on RFID
Gong-kuang zidonghua, 2018 In view of problems of many hidden dangers and weak electromechanical technology of coal mine equipments management, an inspection system for coal mine equipment based on RFID was designed.
CUI Xiguo, HAN An
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
, 2003 The BC Ministry of Sustainable Resource Management (BCMSRM), is undertaking a program of environmental remediation at the Britannia Mine site, located 45km north of Vancouver, BC.
O'Hara, Gerry
core
Criteria for decision-making for the best reclamation solution [PDF]
Podzemni RadoviMine site reclamation is a relevant step in maintaining ecological balance after mining activities. Although mining activities provide many economic benefits, they often have a negative impact on the environment.
Gaćina Radmila +3 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Probability of failure of waste disposals sites in Žirovski vrh uranium mine
Geologija, 2002 The only Uranium mine in Slovenia @irovski vrh was closed in 1990 due to economic reasons. After the closure extensive decommissioning works in the mine and in the surrounding began.
Tomaž Beguš
doaj
Management Systems in Production EngineeringThe main aim of the article is to determine the impact of mine closure on the local environment, with particular emphasis on the social, economic and environmental problems that arise when mining activities are limited or discontinued.
Marszowski Ryszard +1 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source