Results 91 to 100 of about 24,541 (307)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
, 1991 The Highvale Mine is located in Central Alberta, 65 km west of Edmonton. It is the largest of several coal strip mines operating in agricultural areas of Alberta.
Wenzel, E. C. +3 more
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Surface Mine Design and Planning for Lunar Regolith Production
, 2003 Terrestrial surface mine design and planning techniques are applied to the production of lunar regolith for manufacturing makeup gases for the life-support system of a lunar base.
Gertsch, Richard E., Gertsch, Leslie S.
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Social impacts of mine closure : engaging employees and host communities in planning for closure
, 2015 Planning for mine closure usually focuses on a detailed reclamation plan designed by experts to mitigate environmental impacts; however, less is known about the social aspects of mine closure and how to mitigate the socio-economic impacts of closing a ...
Costa, S.
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Gong-kuang zidonghua, 2016 According to present status of coal mine informatization construction in China，the paper analyzed existing problems in coal enterprises informatization construction, such as lack of top-level planning, lagging of standards of coal mine informatization ...
TAN Zhanglu, CHEN Xiao
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Proceedings of the 15th North American Mine Ventilation Symposium
, 2015 These conference proceedings consist of 70 peer-reviewed technical papers representing subjects related to underground mine ventilation. All were presented at the 15th North American Mine Ventilation Symposium (NAMVS) from June 20, 2015 to June 25, 2015,
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REM: International Engineering JournalTo optimize a mining project, it is necessary to deal with several technical aspects and constraints, such as orebody modelling, reserve estimation, blending strategy, optimal and operational pit designs, cost control, environmental issues, among others.
Bruno Tomasi Kuckartz +1 more
doaj +1 more source