Results 81 to 90 of about 24,541 (307)

The mining rate in open pit mine planning [PDF]

open access: yes, 2015
In the mining business, mine planning is the activity that determines the exploitation of a mineral resource with the aim of maximising its intrinsic value. The number of variables that are required to carry out this activity and the complexity of dealing with a finite, non-renewable resource make it difficult to find an optimum solution.
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Balancing focal species, recreation and biodiversity in mountain coal mine closure planning : Alberta, Canada

open access: yes, 2011
Coal extraction in the Coal Branch region of Alberta, Canada has occurred since 1911 with surface mining dominating as of the 1940s. Coal mining in this mountain/foothills landscape now occurs in a multiple land use context along with oil and gas ...
Symbaluk, M.D.   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

An assessment of the quantum for financial provision of mine closures: a Monte Carlo approach.

open access: yes, 2012
Includes abstract.Includes bibliographical references.Poor mine closure policy threatens both society and the environment. Some of the more prominent threats that have manifested are acid mine drainage, slimes dams and toxic dust from dumps.
Hewitson, Shaun B
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Analysis of Mine Mobile Fleet Maintenance vs. Mine Roads Maintenance for Optimum Performance

open access: yes, 2014
The expansion of the mining operations world-wide leads to development of large vehicles. In the past the design of the mine haul roads was done empirically based on the local experience; this way is not applicable anymore because the extreme increase of
Youssef Hamoudeh   +3 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Deposition planning at the Diavik Diamond Mine

open access: yes, 2011
The Diavik Diamond Mine (Diavik), a joint venture of Rio Tinto and Harry Winston, is located on East Island in Lac de Gras in the subarctic climatic region of Canada’s Northwest Territories and has been in operation since 2002.
Cunning, John   +3 more
core  

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