Results 111 to 120 of about 98,174 (313)

Nonlinear evolution characteristics and seepage mechanical model of fluids in broken rock mass based on the bifurcation theory

Scientific Reports
With the deep extension of coal mining in China, fault water inrush has become one of the major disasters threatening the safety production of coal mine.
Jia Yunlong, Cao Zhengzheng, Li Zhenhua, Du Feng, Huang Cunhan, Lin Haixiao, Wang Wenqiang, Zhai Minglei   +7 more
doaj   +1 more source

An experimental study on the yield strength of cement grout for grouting in the limestone area of a coal seam floor

Meitian dizhi yu kantan
Objective and MethodsIn recent years, regional grouting through ground directional drilling has become the preferred technique for water disaster prevention and control in floor limestones in a coal mining area.
Jun ZOU, Yan GUO, Herong GUI, Weimin WANG, Zhenlin CHEN, Faming LIU, Yanan DAI, Yang HU, Zengbao CHEN, Jun LI, Chuan GAO, Heng LI   +11 more
doaj   +1 more source

Mining and Water Pollution [PDF]

, 2012
Residual sulphide minerals, especially pyrite, in the tailings dumps are unstable when exposed to atmospheric oxygen and undergo oxidation resulting in the generation of acid mine drainage (AMD) and the subsequent release of heavy metals and metalloids (Jambor & Blowes, 1998).
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Recognizing Indigenous Water Cultures and Rights in Mine Water Management: The Role of Negotiated Agreements

, 2015
A social licence to operate is increasingly important in the resources industry, particularly with respect to mining activities that might jeopardize water sources on indigenous lands. Negotiated agreements have gained popularity because legal frameworks
Barber, M, Jackson, S
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interaction between an acidic mine water and an agricultural soil material

, 2008
A column filtering experiment was conducted to investigate interaction between an acidic mine water and an agricultural soil material during percolation of the mine water through the soil column.
Lu, W., Lin, C., Li, J., Chen, H., Chen, A., Ma, Y., Bai, Y.   +6 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Three-dimensional spatial identification and risk quantitative assessment of spontaneous combustion hazard sources in coal gangue dumps

Meitan kexue jishu
The spontaneous combustion of coal gangue poses a serious threat to the ecological restoration of gangue dumps and the safe utilization of resources.
Shoucheng ZHANG, Honglei LIU, Qiang WU, Zhengmeng GUO, Shuai ZHANG, Shuyang WANG   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source