Results 81 to 90 of about 98,174 (313)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A new determination method of hydraulic support resistance in deep coal pillar working face
Scientific ReportsThis study addresses hydraulic support resistance determination in deep coal pillar caving faces at Zhaogu No. 2 Mine through integrated theoretical, numerical, and field analyses. Theoretical calculations (empirical estimation: ≥ 15.742 MN; dynamic load
Guo-Dong Li +5 more
doaj +1 more source
CrystalsCohesive soil in the reservoir area is vulnerable to natural disasters because of its poor erosion resistance and low strength. Therefore, it needs to be reinforced.
Xinfa Li, Dingxiang Zhuang, Ru Hu
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
CrystalsThe mechanism of dolomite has been a major hotspot in geological research. However, most of the current studies mainly focus on single microorganisms and fail to fully consider the influence of marine microbial diversity on the precipitation of carbonate
Dingxiang Zhuang +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Field application and diffusion law of grouting slurry in floor aquifer of a coal mine
Scientific ReportsFloor aquifers are responsible for approximately 55% of water inrush incidents in coal mines. As mining depths increase, the risk posed by confined floor aquifers becomes more severe.
Cao Zhengzheng +6 more
doaj +1 more source
Meitan kexue jishuChina is short of natural gas resources, and these low-permeable reservoirs (such as tight gas, shale gas and coalbed methane) being difficultly developed account for a large proportion. How to efficiently developed this part of strategic resources is of
Chuanlong DONG +2 more
doaj +1 more source
Variability in Mine Waste Mineralogy and Water Environment Risks: a Case Study on the River Almond Catchment, Scotland [PDF]
, 2021 The River Almond catchment contains coal, oil shale and ironstone mine waste and displays widespread surface water metals pollution. Mineralogical investigations and geochemical modelling at four mine waste sites identified pyrite oxidation and jarosite,
Haunch, Simon +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source