Results 1 to 10 of about 93,504 (350)

3D model of amphioxus steroid receptor complexed with estradiol [PDF]

open access: yes, 2009
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
David J. Chang, Michael E. Baker
core   +2 more sources

Glucocorticoid and Mineralocorticoid Receptors in the Brain: A Transcriptional Perspective

open access: yesJournal of the Endocrine Society, 2019
Adrenal glucocorticoid hormones are crucial for maintenance of homeostasis and adaptation to stress. They act via the mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs)—members of the family of nuclear receptors. MRs and GRs can mediate
Anne M. Koning   +3 more
semanticscholar   +1 more source

Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in rat heart through mineralocorticoid receptor blockade. [PDF]

open access: yesPLoS ONE, 2014
Aldosterone administration in rats results in several cardiac alterations. Previous studies have demonstrated that proanthocyanidins, phenolic bioactive compounds, have cardioprotective effects.
Beatriz Martín-Fernández   +7 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

open access: yes, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

open access: yes, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin   +13 more
core   +4 more sources

Expression of genes encoding mineralocorticoid biosynthetic enzymes and the mineralocorticoid receptor, and levels of mineralocorticoids in the bovine follicle and corpus luteum

open access: yesThe Journal of Reproduction and Development, 2019
Unlike sex steroids, mineralocorticoids have attracted limited attention in ovarian physiology. Recent studies on primates have indicated possible local synthesis and action of mineralocorticoids in the ovary.
Memory MUKANGWA   +4 more
doaj   +1 more source

Adipocytes, aldosterone and obesity-related hypertension [PDF]

open access: yes, 2016
Understanding the mechanisms linking obesity with hypertension is important in the current obesity epidemic as it may improve therapeutic interventions.
Friederich-Persson, Malou   +3 more
core   +1 more source

Physiological monitoring in the complex multi-morbid heart failure patient - Introduction. [PDF]

open access: yes, 2019
Repeated physiological monitoring of comorbidities in heart failure (HF) is pivotal. This document introduces the main challenges related to physiological monitoring in the complex multimorbid HF patient, arising during an ESC consensus meeting on this ...
Rosano, GMC, Seferović, PM
core   +1 more source

Aldosterone Regulates Pendrin and Epithelial Sodium Channel Activity through Intercalated Cell Mineralocorticoid Receptor-Dependent and -Independent Mechanisms over a Wide Range in Serum Potassium.

open access: yesJournal of the American Society of Nephrology, 2020
BACKGROUND Aldosterone activates the intercalated cell mineralocorticoid receptor, which is enhanced with hypokalemia. Whether this receptor directly regulates the intercalated cell chloride/bicarbonate exchanger pendrin is unclear, as are potassium's ...
T. Pham   +9 more
semanticscholar   +1 more source

Parathyroid localization [PDF]

open access: yes, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.   +7 more
core   +1 more source

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