Results 11 to 20 of about 43,749 (262)
The role of aldosterone in the pathogenesis of diabetic retinopathy
Frontiers in Endocrinology, 2023 Aldosterone, as a mineralocorticoid of adrenal origin, has effects that are not limited to the urinary tract. As an important regulator in Vasoactive hormone pathways, aldosterone may play an effect in the pathogenesis of diabetic retinopathy (DR ...
Kangcheng Liu +8 more
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Pharmacology Research & Perspectives, 2022 Aldosterone exerts some of its effects not by binding to mineralocorticoid receptors, but rather by acting via G protein‐coupled estrogen receptors (GPER).
Qingming Ding +5 more
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Trials, 2011 Background Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one study, hydrocortisone for treatment
Asehnoune Karim +3 more
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Aldosterone Blocks Rat Stem Leydig Cell Development In Vitro
Frontiers in Endocrinology, 2018 Aldosterone (ALDO) is a primary endogenous mineralocorticoid, appearing as the main hormone controlling sodium and water homeostasis. Its emerging role in the development of many organs has gained interest over the past few years.
Jingwei Zhang +9 more
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Physiological Reports, 2021 Restricting dietary sodium promotes sodium appetite in rats. Prolonged sodium restriction increases plasma potassium (pK), and elevated pK is largely responsible for a concurrent increase in aldosterone, which helps promote sodium appetite.
Frederico S. Fazan +3 more
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Mineralocorticoid resistance [PDF]
Clinical Endocrinology, 2005 SummaryThe mineralocorticoid aldosterone plays a crucial role in regulation of volume and electrolyte homeostasis. In recent years there has been considerable progress in deciphering the role of aldosterone in human physiology by the study of monogenic disorders exhibiting mineralocorticoid resistance. Although these disorders are rare, the elucidation
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Vascular cell‐specific roles of mineralocorticoid receptors in pulmonary hypertension
Pulmonary Circulation, 2021 Abnormalities that characterize pulmonary arterial hypertension include impairment in the structure and function of pulmonary vascular endothelial and smooth muscle cells.
Divya P. Menon +10 more
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Eight weeks of mineralocorticoid blockade does not improve insulin sensitivity in type 2 diabetes
Physiological Reports, 2021 Individuals with type 2 diabetes have an increased risk of cardiovascular disease. A correlation between plasma aldosterone and hyperinsulinemia has been demonstrated in vivo, and hyperinsulinemia and insulin resistance are independently associated with ...
Stine H. Finsen +4 more
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Localization of mineralocorticoid receptors at mammalian synapses. [PDF]
PLoS ONE, 2010 In the brain, membrane associated nongenomic steroid receptors can induce fast-acting responses to ion conductance and second messenger systems of neurons.
Eric M Prager +4 more
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The Journal of Reproduction and Development, 2019 Unlike sex steroids, mineralocorticoids have attracted limited attention in ovarian physiology. Recent studies on primates have indicated possible local synthesis and action of mineralocorticoids in the ovary.
Memory MUKANGWA +4 more
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