Results 1 to 10 of about 46,446 (218)

Bilateral Adrenal Masses with Different Aetiologies Presenting as Addisonian Crisis with Acute Kidney Injury: A Case Series [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
An Addisonian Crisis (AC) is an endocrinological emergency associated with high mortality, resulting from an acute deficit of hormones from the adrenal glands.
Mohini   +4 more
doaj   +1 more source

Aldosterone Inhibits In Vitro Myogenesis by Increasing Intracellular Oxidative Stress via Mineralocorticoid Receptor [PDF]

open access: yesEndocrinology and Metabolism, 2021
Background Despite clinical evidence indicating poor muscle health in subjects with primary aldosteronism (PA), it is still unclear whether the role of aldosterone in muscle metabolism is direct or mediated indirectly via factors, such as electrolyte ...
Jin Young Lee   +5 more
doaj   +1 more source

case of liquorice-infused marijuana causing syndrome of apparent mineralocorticoid excess

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Marijuana has long been used both for recreational and medicinal purposes. Most of the available forms of marijuana contain additives such as liquorice to enhance its flavour. Liquorice increases the amounts of cortisol in the body and produces metabolic
Asnia Latif   +2 more
doaj   +1 more source

Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The pathobiology of heart failure with preserved ejection fraction (HFpEF) is still poorly understood, and effective therapies remain limited.
Bence Hegyi   +9 more
doaj   +1 more source

Heterogeneous natural history of Addison’s disease: mineralocorticoid deficiency may predominate

open access: yesEndocrine Connections, 2022
Autoimmune Addison’s disease (AAD) is defined as primary adrenal insufficiency due to immune-mediated destruction of the adrenal cortex. This destruction of steroid-producing cells has historically been thought of as an irreversible process, with linear ...
Sophie Howarth   +3 more
doaj   +1 more source

New Perspectives on Sex Steroid and Mineralocorticoid Receptor Signaling in Cardiac Ischemic Injury

open access: yesFrontiers in Physiology, 2022
The global burden of ischemic heart disease is burgeoning for both men and women. Although advances have been made, the need for new sex-specific therapies targeting key differences in cardiovascular disease outcomes in men and women remains ...
Laura A. Bienvenu   +7 more
doaj   +1 more source

Clinical features and long‐term management of cats with primary hypoadrenocorticism using desoxycorticosterone pivalate and prednisolone

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Primary hypoadrenocorticism (PH) is rare in cats and knowledge about treatment is sparse. Objective To describe cats with PH with a focus on long‐term treatment. Animals Eleven cats with naturally occurring PH.
Nadja S. Sieber‐Ruckstuhl   +8 more
doaj   +1 more source

The role of aldosterone in the pathogenesis of diabetic retinopathy

open access: yesFrontiers in Endocrinology, 2023
Aldosterone, as a mineralocorticoid of adrenal origin, has effects that are not limited to the urinary tract. As an important regulator in Vasoactive hormone pathways, aldosterone may play an effect in the pathogenesis of diabetic retinopathy (DR ...
Kangcheng Liu   +8 more
doaj   +1 more source

Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist

open access: yesPharmacology Research & Perspectives, 2022
Aldosterone exerts some of its effects not by binding to mineralocorticoid receptors, but rather by acting via G protein‐coupled estrogen receptors (GPER).
Qingming Ding   +5 more
doaj   +1 more source

Corticotherapy for traumatic brain-injured Patients - The Corti-TC trial: study protocol for a randomized controlled trial

open access: yesTrials, 2011
Background Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one study, hydrocortisone for treatment
Asehnoune Karim   +3 more
doaj   +1 more source

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