Results 121 to 130 of about 46,446 (218)

Pulmonary Vein Isolation Alone Versus Adjunctive Ablation for Paroxysmal Atrial Fibrillation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Clinical Outcomes of Pulmonary Vein Isolation Alone Versus Additional Lesion Sets in Paroxysmal Atrial Fibrillation ABSTRACT Background Pulmonary vein isolation (PVI) is the standard ablation strategy for paroxysmal atrial fibrillation (PAF). Despite guideline recommendations favoring PVI alone in PAF, some operators routinely perform extra pulmonary ...
Michel Abou Khalil   +17 more
wiley   +1 more source

Temporal Association Between Intrathoracic Impedance and Tachyarrhythmia Occurrence

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
A decrease in intrathoracic impedance is temporally associated with subsequent AF occurrence and, at the episode level, with a shorter time to VT. These findings suggest that daily intrathoracic impedance may provide information on short‐term changes preceding tachyarrhythmia occurrence.
Monika Butkuvienė   +5 more
wiley   +1 more source

Effects of esaxerenone add‐on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Makoto Ohara   +9 more
wiley   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura   +6 more
wiley   +1 more source

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa   +13 more
wiley   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan   +5 more
wiley   +1 more source

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