Results 131 to 140 of about 43,749 (262)
Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe +4 more
wiley +1 more source
Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular-Kidney-Metabolic Syndrome. [PDF]
Zeitler E +4 more
europepmc +1 more source
Take my breath away: Defining the oxygen saturation threshold for fish cortisol stress response
Abstract Human activities are affecting the number, size and severity of hypoxic zones in aquatic ecosystems. As oxygen is one of the most important abiotic factors affecting fish biology, exposure to low levels of dissolved oxygen may lead to a reduction in fitness.
Sébastien Alfonso +4 more
wiley +1 more source
Finerenone in mildly reduced or preserved ejection fraction and chronic kidney disease: a narrative review. [PDF]
Faheem MSB +4 more
europepmc +1 more source
ABSTRACT Introduction Preprocedural imaging can improve the success rate of ventricular tachycardia (VT) ablation. Left ventricular wall thickness (LVWT) measured by cardiac computed tomography (CT) can be used to identify infarct regions. We sought to determine whether an association exists between left ventricular wall thickness (LVWT) as obtained ...
Alwin B. P. Noordman +4 more
wiley +1 more source
ABSTRACT Background The role of cardiac resynchronization therapy (CRT) during hospitalization for heart failure (HFH) is uncertain, because hospitalized patients were routinely excluded from landmark CRT trials. Despite this, CRT implantation during HFH is common.
Oliver Rees +5 more
wiley +1 more source
Cardiovascular-kidney-metabolic (CKM) syndrome. [PDF]
Dwyer KM, Figtree PE, Oetsch K, Gupta A.
europepmc +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Residual risk in cardiovascular and renal diseases and the potential role of aldosterone synthase inhibitors. [PDF]
Umanath K, Dwyer JP, Mentz RJ.
europepmc +1 more source
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed +8 more
wiley +1 more source

