Results 31 to 40 of about 31,334 (301)
Nuclear receptors in vascular biology [PDF]
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla +56 more
core +3 more sources
A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI [PDF]
BACKGROUND: Acute kidney injury (AKI) is a frequent condition in hospitalised patients undergoing major surgery or the critically ill and is associated with increased mortality.
Delles, C. +6 more
core +3 more sources
The role of aldosterone in the development of atrial fibrillation: modern understanding of problem
The review of literature presents modern ideas about the role of aldosterone in the development and maintenance of atrial fibrillation. It is shown that hormone takes part in all stages of the electrophysiological and structural atrial remodeling ...
N. T. Vatutin +2 more
doaj +1 more source
Glucocorticoid feedback paradox: a homage to Mary Dallman
As the end product of the hypothalamus-pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone coordinate circadian activities, stress-coping, and adaptation to change.
Edo Ronald de Kloet
doaj +1 more source
The renin-angiotensin-aldosterone system (RAAS) activation plays a key role in the chronic kidney disease (CKD) progression and in the cardiovascular complications (CVC) development in patients with diabetes mellitus (DM).
Irina N. Bobkova
doaj +1 more source
Aldosterone: Essential for Life but Damaging to the Vascular Endothelium
The renin angiotensin aldosterone system is a key regulator of blood pressure. Aldosterone is the final effector of this pathway, acting predominantly via mineralocorticoid receptors. Aldosterone facilitates the conservation of sodium and, with it, water
Michael Crompton +3 more
doaj +1 more source
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin +13 more
core +9 more sources
The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet +4 more
core +1 more source
Pseudohypoaldosteronism Type I: A Report of Two Cases
Pseudohypoaldosteronism (PHA) i s characterised by salt wasting and failure to thrive in the newborn because of the resistance of mineralocorticoid receptors to aldosterone.
Enver Şimşek, Kenan Kocabay
doaj
The article focuses on the negative role of hyperaldosteronism in cardiovascular diseases and the possibility of its control when using a selective mineralocorticoid receptor antagonist – eplerenone.
A. G. Evdokimova +3 more
doaj +1 more source

