Results 41 to 50 of about 31,334 (301)

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]

open access: yes, 2007
We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark   +7 more
core   +1 more source

Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]

open access: yes, 2000
Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J.,   +6 more
core   +1 more source

Parathyroid localization [PDF]

open access: yes, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.   +7 more
core   +1 more source

Treatment of Hypertension in a Child With 11Beta-Hydroxylase Deficiency: A Case Report

open access: yesJournal of Pediatrics Review, 2022
Background: 11beta-hydroxylase deficiency (11βOHD) is clinically presented with external genitalia virilization in girls and precocious puberty in boys. Low renin hypertension occurs in both sexes.
Fatemeh Saffari, Banafsheh Arad
doaj  

The Promiscuous Mineralocorticoid Receptor [PDF]

open access: yesHypertension, 2016
See related article, pp 897–905 The article by Briet et al1 in this issue, “Aldosterone-induced vascular remodeling and endothelial dysfunction require functional angiotensin type 1a receptors,” represents a prodigious amount of work by the authors: it is not surprising that the first 3 are credited as having equally contributed. The authors build on
openaire   +2 more sources

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

open access: yes, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C.   +8 more
core   +1 more source

The Dark Side of Licorice Consumption

open access: yesAnnals of Internal Medicine: Clinical Cases
Licorice-induced apparent mineralocorticoid excess is a rare but reversible cause of hypertension and hypokalemia. Glycyrrhizic acid (GA), found in licorice, inhibits 11β-HSD2, increasing renal cortisol and activating mineralocorticoid receptors.
Rojah Thayabaran   +3 more
doaj   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

open access: yes, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF   +3 more
core   +2 more sources

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

open access: yes, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy