Results 71 to 80 of about 7,219 (278)
ESC Heart Failure, Volume 12, Issue 2, Page 888-899, April 2025.Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki +11 more
wiley +1 more source
The Evolution of Mineralocorticoid Receptors [PDF]
Molecular Endocrinology, 2006 Abstract When the human mineralocorticoid receptor (hMR) was cloned and sequenced by the Evans laboratory, its close homology with the human glucocorticoid receptor (hGR) was noted; subsequently, on the basis of its higher sequence similarity to the GR than to the progesterone receptor (PR) or androgen receptor (AR), MR and GR have ...
Xiao, Hu, John W, Funder
openaire +2 more sources
Mineralocorticoids and sodium in chronic kidney disease - regulation and cardiovascular implications [PDF]
, 2012 Chronic kidney disease is common and associated with an elevated cardiovascular risk, as well as the long-term risk of renal failure. At present, therapeutic approaches to managing chronic kidney disease (CKD) do not fully reverse these risks.
McQuarrie, Emily Pamela
core +1 more source
Escape from the sodium-retaining effects of mineralocorticoids [PDF]
, 1980 The prolonged administration of pharmacologic doses of mineralocorticoids to normal subjects results in hypokalemia, metabolic alkalosis, polydipsia, polyuria, and transient sodium retention.
Strand, James C. +4 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 998-1012, April 2025.In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro +15 more
wiley +1 more source
Acta Medica Iranica, 1996 - Pseudohypoaldosteronism (P'HA) is referred to a state of endorgan unresponsiveness to aldosterone. In this article a 12 day - old mule newborn is presented with hyponatremia, hyperkalemia and metabolic acidosis.
A. Rabbani., B. Goharfar, A. Dehgani
doaj +2 more sources
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe
ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani +11 more
wiley +1 more source
Familial Mineralocorticoid Induced Hypertension in the Sultanate of Oman
Sultan Qaboos University Medical Journal, 2008 Objectives: In Oman, many hypertensive patients with a family history of the disease respond to treatment with spironolactone, a mineralocorticoid receptor (MC-R) blocking agent thus suggesting a high prevalence of mineralocorticoid (MC) induced disease.
Nicholas JY Woodhouse +3 more
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