Results 261 to 270 of about 1,341,600 (296)

The minimal important difference for measures of urticaria disease activity: Updated findings

Allergy and Asthma Proceedings, 2015
The Urticaria Patient Daily Diary (UPDD) is a validated patient-reported outcome that captures key measures of urticaria disease activity.To update estimates of the minimal important difference (MID) for urticaria disease activity measures in the UPDD, including the weekly itch severity score, weekly number of hives score, weekly average size of ...
Susan D, Mathias, Ross D, Crosby, Karin E, Rosén, James L, Zazzali   +3 more
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Minimal Disease Activity and Anti–Tumor Necrosis Factor Therapy in Psoriatic Arthritis

Arthritis Care & Research, 2015
ObjectiveA state of minimal disease activity (MDA) was defined and validated as target for treatment in psoriatic arthritis (PsA). We aimed to identify disease characteristics, outcome, and predictors of MDA in patients treated with tumor necrosis factor α (TNFα) blockers.MethodsPatients fulfilling the Classification of Psoriatic Arthritis criteria ...
Amir, Haddad, Arane, Thavaneswaran, Ioana, Ruiz-Arruza, Fawnda, Pellett, Vinod, Chandran, Richard J, Cook, Dafna D, Gladman   +6 more
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Minimal disease activity for rheumatoid arthritis: a preliminary definition.

The Journal of rheumatology, 2005
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of patients achieving a satisfactory state of minimal disease activity (MDA) is becoming a more important measure with which to compare different treatment ...
Wells, George A., Boers, Maarten, Shea, Beverley, Brooks, Peter M., Simon, Lee S., Strand, C. Vibeke, Aletaha, Daniel, Anderson, Jennifer J., Bombardier, Claire, Dougados, Maxime, Emery, Paul, Felson, David T., Fransen, Jaap, Furst, Dan E., Hazes, Johanna M.W., Johnson, Kent R., Kirwan, John R., Landewé, Robert B.M., Lassere, Marissa N.D., Michaud, Kaleb, Suarez-Almazor, Maria, Silman, Alan J., Smolen, Josef S., Van Der Heijde, Desiree M.F.M., Van Riel, Piet L.C.M., Wolfe, Fred, Tugwell, Peter S.   +26 more
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Low disease activity state in rheumatoid arthritis: concepts and derivation of minimal disease activity.

Clinical and experimental rheumatology, 2007
With recent advances in therapy, the proportion of patients achieving a satisfactory state of minimal disease activity (MDA) is becoming a more important measure with which to compare different treatment strategies. MDA is between high disease activity and remission and anyone in remission will also be in MDA.
G, Wells, M, Boers, P, Tugwell
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Prostate Cancer: New Insights into Minimal and Localised Disease: Active Surveillance

European Urology Supplements, 2009
This paper summarises current views on active surveillance as presented during the session titled, ‘‘Prostate Cancer: New Insights to Minimal and Localised Disease,’’ at the 2nd World Congress on Controversies in Urology (CURy) in Lisbon, Portugal.
Kirkali, Ziya, Fleshner, Neil, Boccon-Gibod, Laurent   +2 more
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Treating Psoriatic Arthritis to Target: Defining the Psoriatic Arthritis Disease Activity Score That Reflects a State of Minimal Disease Activity

The Journal of Rheumatology, 2019
Objective.The Psoriatic Arthritis Disease Activity Score (PASDAS) is a composite disease activity measure (range 0–10) for psoriatic arthritis (PsA). We aimed to validate a cutoff value of PASDAS that defines minimal disease activity (MDA) state, as well as to validate previously defined PASDAS cutoffs for low and high disease activity.Methods.Patients
Anthony V. Perruccio, Matthew Got, Suzanne Li, Yang Ye, Dafna D. Gladman, Vinod Chandran   +5 more
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CTL-defined Cancer Vaccines: Perspectives for Active Immunotherapeutic Interventions in Minimal Residual Disease

Cancer and Metastasis Reviews, 1999
The characterization of tumor-associated antigens recognized by cellular or humoral effectors of the immune system has opened new perspectives for cancer therapy. Several categories of cancer-associated antigens have been described as targets for cytotoxic T lymphocytes (CTL) in vitro and in vivo: (1) 'Cancer-Testis' (CT) antigens expressed in ...
E, Jäger, D, Jäger, A, Knuth
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Altered activity of plasma hemopexin in patients with minimal change disease in relapse

Pediatric Nephrology, 2005
Since an active isoform of plasma hemopexin (Hx) has been proposed to be a potential effector molecule in minimal change disease (MCD), we tested plasma and urine samples from subjects with MCD in relapse (n = 18) or in remission (n = 23) (after treatment with prednisolone) for presence or activity of Hx.
Bakker, Winston W., van Dael, Catharina M.L., Pierik, Leonie J.W.M., van Wijk, Joanna A.E., Nauta, Jeroen, Borghuis, Theo, Kapojos, Jola J.   +6 more
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Defining minimal disease activity in psoriatic arthritis: a proposed objective target for treatment

Annals of the Rheumatic Diseases, 2010
To create minimal disease activity (MDA) criteria for psoriatic arthritis (PsA). With recent therapeutic advances, this is now a goal for treatment and may represent a measure to compare therapies. It defines a satisfactory state of disease activity rather than a change, and encompasses all aspects of the disease.40 patient profiles were sampled from ...
Coates, L.C., Fransen, J., Helliwell, P.S.   +2 more
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Immunotherapy of Minimal Residual Disease by Immunocompetent Lymphocytes and Their Activation by Cytokines

Cancer Investigation, 1992
A murine model of minimal residual disease (MRD) was established utilizing the murine B-cell leukemia (BCL1). BALB/c mice inoculated with up to 10(4) BCL1 were cured (greater than 1 year disease-free survival) following administration of intraperitoneal injections of recombinant human IL-2 (10(5) Cetus units x 3/day intraperitoneally x 5 days ...
S, Slavin, A, Ackerstein, L, Weiss, A, Nagler, R, Or, E, Naparstek   +5 more
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