Results 91 to 100 of about 656,371 (370)

Curative outcomes following blinatumomab in adults with minimal residual disease B-cell precursor acute lymphoblastic leukemia

open access: yesLeukemia and Lymphoma, 2020
Minimal residual disease (MRD) is the strongest predictor of relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In BLAST study (NCT01207388), adults with BCP-ALL in remission with MRD after chemotherapy received blinatumomab, a CD19 BiTE®
N. Gökbuget   +14 more
semanticscholar   +1 more source

Handling Label Uncertainty on the Example of Automatic Detection of Shepherd's Crook RCA in Coronary CT Angiography [PDF]

open access: yesarXiv, 2023
Coronary artery disease (CAD) is often treated minimally invasively with a catheter being inserted into the diseased coronary vessel. If a patient exhibits a Shepherd's Crook (SC) Right Coronary Artery (RCA) - an anatomical norm variant of the coronary vasculature - the complexity of this procedure is increased. Automated reporting of this variant from
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Advances in the assessment of minimal residual disease in mantle cell lymphoma

open access: yesJournal of Hematology & Oncology, 2020
The clinical impact of minimal residual disease detection at early time points or during follow-ups has been shown to accurately predict relapses among patients with lymphomas, mainly in follicular and diffuse large B cell lymphoma.
Dayoung Jung   +3 more
doaj   +1 more source

Day +60 WT1 assessment on CD34 selected bone marrow better predicts relapse and mortality after allogeneic stem cell transplantation in acute myeloid leukemia patients

open access: yesFrontiers in Oncology, 2022
The aim of this study was to evaluate the role of WT1 expression after allogeneic stem cell transplantation (alloHSCT) in patients with acute myeloid leukemia (AML). We studied WT1 expression in bone marrow cells from 50 patients in complete remission on
Patrizia Chiusolo   +20 more
doaj   +1 more source

Minimal Residual Disease Assessment in the Context of Multiple Myeloma Treatment [PDF]

open access: yes, 2016
With contemporary therapeutic strategies in multiple myeloma, heretofore unseen depth and rate of responses are being achieved. These strategies have paralleled improvements in outcome of multiple myeloma patients.
Jinming Song   +2 more
core   +1 more source

Imaging of treatment response and minimal residual disease in multiple myeloma: state of the art WB-MRI and PET/CT

open access: yesSkeletal Radiology, 2021
Bone imaging has been intimately associated with the diagnosis and staging of multiple myeloma (MM) for more than 5 decades, as the presence of bone lesions indicates advanced disease and dictates treatment initiation. The methods used have been evolving,
F. Lecouvet   +12 more
semanticscholar   +1 more source

Evidence synthesis with reconstructed survival data [PDF]

open access: yesarXiv, 2022
We present a general approach to synthesizing evidence of time-to-event endpoints in meta-analyses of aggregate data (AD). Our work goes beyond most previous meta-analytic research by using reconstructed survival data as a source of information. A Bayesian multilevel regression model, called the "meta-analysis of reconstructed survival data" (MARS), is
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

The Role and Impact of Minimal Residual Disease in NSCLC

open access: yesCurrent Oncology Reports, 2021
There has been a huge development in the assessment of malignancies through liquid biopsies last years, especially for NSCLC, where its use has become part of clinical practice in some settings. We aim to summarize current evidence about minimal residual
D. Frisone, A. Friedlaender, A. Addeo
semanticscholar   +1 more source

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