Results 101 to 110 of about 6,414,902 (294)
Minimal Residual Disease in Chronic Lymphocytic Leukemia: A New Goal?
Frontiers in Oncology, 2019 In chronic lymphocytic leukemia (CLL), there is a growing interest for minimal residual disease (MRD) monitoring, due to the availability of drug combinations capable of unprecedented complete clinical responses.
Ilaria Del Giudice +11 more
doaj +1 more source
Monitoring actuator failures for a large transprot aircraft - the nominal case [PDF]
, 2009 We consider the problem of designing residual generators with least dynamical orders to solve actuator fault detection and isolation problems for a generic large transport aircraft.
Varga, Andreas
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Ultrasensitive detection of acute myeloid leukemia minimal residual disease using single molecule molecular inversion probes [PDF]
, 2017 The identification of minimal residual disease is the primary diagnostic finding which predicts relapse in patients treated for acute myeloid leukemia. Ultrasensitive detection of minimal residual disease would enable better patient risk stratification ...
Stephen J. Salipante +4 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Minimal residual disease [PDF]
Bone Marrow Transplantation, 2001 T. Szczepański, J.J.M. van Dongen
+5 more sources
New computational approach for the design of fault detection and isolation filters [PDF]
, 2003 We propose a numerically reliable computational approach for the design of residual generators for fault detection and isolation filters. The new approach is based on computing solutions of least dynamical orders of linear equations with rational matrix ...
Varga, Andras
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Role of minimal residual disease assessment in multiple myeloma
HaematologicaMultiple myeloma (MM) is a hematologic malignancy characterized by clonal proliferation of plasma cells. MM is a heterogeneous disease, featured by various molecular subtypes with different outcomes. With the advent of very efficient therapies including
Raphael Szalat +2 more
doaj +1 more source
Haematologica, 2009 Resistance to therapeutic agents is a major factor in the failure of cancer treatments. In leukemia, the resistant cells remaining in the bone marrow and/or peripheral blood constitute minimal residual disease and are detectable by highly sensitive ...
Marie C. Béné, Jaspal S. Kaeda
doaj +1 more source