Results 91 to 100 of about 236,269 (292)
Identification of residual leukemic cells by flow cytometry in childhood B-cell precursor acute lymphoblastic leukemia: verification of leukemic state by flow-sorting and molecular/cytogenetic methods
Haematologica, 2012 Reduction in minimal residual disease, measured by real-time quantitative PCR or flow cytometry, predicts prognosis in childhood B-cell precursor acute lymphoblastic leukemia.Nina F. Øbro, Lars P. Ryder, Hans O. Madsen, Mette K. Andersen, Birgitte Lausen, Henrik Hasle, Kjeld Schmiegelow, Hanne V. Marquart +7 moredoaj +1 more sourceModulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári +6 morewiley +1 more sourceFrom mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato +2 morewiley +1 more sourceA certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real time quantitative PCR [PDF]
, 2015 Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results reported by different laboratories.Mitterbauer, G., Kim, D.-W., S McCarron, Polakova, K.M., Hall, V, Preudhomme, C., K M Polakova, Hall, V., Schimmel, Heinz G., Cross, N.CP., L Foroni, Gerrard, G., Waits, Paula S., Cross, N.C.P., Jansson, Mattias,, Polakova, Km, Ozbek, U (Ugur), E O Leibundgut, El Housni, Hakim, R Ganderton, E Gineikienė, G Martinelli, Kizilors, A., White, H., Corbisier, P., Hayette, S, Colomer, D., Ganderton, R., Mueller, M. C., Kim, D-W, Van der Velden, V. H. J., de Lange, T, P Waits, Wilson, G., Mitterbauer Hohendanner, G, Cross, Nicholas C P., J Nomdedéu, Nagar, M, Nagar, M., Merle, P. A., Clench, T, Müller, M.C., Hochhaus, A., Fletcher, L, Deprez, Ludovic, Milner, B., Jurcek, Tomas, Nymoen, D. A., Andrikovics, H., T Sacha, Touloumenidou, Tasoula, Cayuela, J-M, Boeckx, N., Merle, Pauline A., Lange, T, Emons, H, Wang, L., Wang, L, D-W Kim, T Jurcek, Touloumenidou, T, Trapmann, Stefanie, A Aggerholm, Gineikiene, Eglė, Barbany, G., McCarron, S., V Kairisto, Mazoua, S., Schimmel, H, Polakova, K M, S Hayette, White, H, Barbany, G, H White, C Preudhomme, Cayuela, Jm, G Romeo, R Talmaci, Lin, Feng, K Zoi, Aggerholm, A, Lion, T, Akiki, S., Jurcek, T., Kairisto, V, A Kizilors, IZZO, BARBARA, Aggerholm, A., Van der Velden, Vh, Mueller, MC, F Lin, Colomer, D, Leibundgut, E O, Hochhaus, A, J Farrugia, Müller, Mc, Milner, B, G Mitterbauer-Hohendanner, Trapmann, S., Leibundgut, Eo, U Ozbek, Waits, P., Daraio, Filomena, Farrugia, J., Nomdedéu, J, Kizilors, Aytug, Preudhomme, C, Wilson, Gillian A., Ozbek, U, Lange, Thoralf, H Andrikovics, Andrikovics, H, El Housni, H, Emons, Hendrik, Deprez, L., Kim, Dong-Wook, Lin, F., Wilkinson, E., S Chudleigh, Dulucq, S., Schimmel, H., Izzo, B., D Colomer, Hayette, S., D Wren, Corbisier, Philippe, P Johnels, Cross, Nc, M Nagar, Zoi, K, V H J Van der Velden, N Boeckx, Bench, Anthony J., Aggerholm, Anni, El Housni, H., Gineikienė, E, H El Housni, Catherwood, M., Kairisto, Veli, Nagar, Meital, Catherwood, Mark Alexander, Hall, Victoria J., Wang, Lihui, Pfeifer, H, R Zadro, Milner, Benedict J., Nymoen, Dag André, Zadro, Renata, Leibundgut, E. O., Kim, Dw, S Trapmann, Fletcher, L., Kairisto, V., Daraio, F, Romeo, Giuliana, K Raudsepp, Akiki, S, Lin, F, L Wang, M Catherwood, Van der Velden, V.H.J., Dulucq, S, Wilson, G, M Jansson, Hochhaus, Andreas, Merle, P A, Nickless, Guillermina, Pajič, T, van der Velden, Vincent, Jansson, M, T Clench, Bench, A, Nomdedéu, Josep, T Touloumenidou, Universitat Autònoma de Barcelona. Departament de Medicina, Müller, M C, Deprez, L, Romeo, G, Foroni, L, Raudsepp, K, Mazoua, Stéphane, Wren, Dörte, Hayette, Sandrine, A Hochhaus, Machová Polakova, Katerina Machová, Foroni, L., Mitterbauer-Hohendanner, G, S Mazoua, Catherwood, M, Cayuela, J.M., Ziermann, Janine, F Daraio, S Dulucq, Sacha, T, Chudleigh, Sandra, G Gerrard, Chudleigh, S, G Wilson, Gerrard, Gareth, Farrugia, J, B Milner, M C Müller, P A Merle, Wilkinson, E, L Fletcher, Emons, H., Polakova, K. M., V Hall, Van der Velden, V.HJ., Wren, D., Nickless, G, Pajič, T., Sacha, T., Cross, N C P, Merle, Pa, Pfeifer, Heike, Merle, P.A., Ziermann, J, Touloumenidou, T., Zoi, K., Cross, NCP, Lion, Thomas, Trapmann, S, Wren, D, El Akiki, Susanna, McCarron, S, H Pfeifer, Corbisier, P, Wilkinson, Elizabeth, Pfeifer, H., Jurcek, T, Johnels, P., Boeckx, Nancy, Gerrard, G, N C P Cross, Ziermann, J., Leibundgut, O., Zadro, R., Martinelli, G., Colomer, Dolors, Izzo, B, White, Helen E., Romeo, G., T Pajič, Farrugia, Joanna, H Emons, P Corbisier, A Bench, Lange, T., G Barbany, Foroni, Letizia, Ganderton, Rosalind H., Raudsepp, K., Mitterbauer-Hohendanner, G., J Ziermann, Martinelli, G, Waits, P, Clench, Tim, Ganderton, R, Daraio, F., Zadro, R, H Schimmel, Kim, D-W., Johnels, Petra, Fletcher, Linda, G Nickless, D A Nymoen, Chudleigh, S., Talmaci, R., Mazoua, S, Nymoen, Da, Oppliger Leibundgut, Elisabeth, T Lion, Bench, A., Dulucq, Stéphanie, Clench, T., Nickless, G., Gineikienė, E., L Deprez, E Wilkinson, Zoi, Katerina, Boeckx, N, Nymoen, D.A., Leibundgut, E.O., T Lange, Nymoen, D A, J-M Cayuela, Mueller, M.C., Johnels, P, Barbany-Bustinza, Gisela, Sacha, Tomasz, Jansson, M., Mitterbauer-Hohendanner, Gerlinde Juliane, Lion, T., Müller, Martin Christian, Van der Velden, VHJ, Cayuela, J-M., B Izzo, Kizilors, A, Kim, D.W., Van der Velden, V H J, Van der Velden54, V.H.J., Cayuela, Jean Michel, Ozbek, U., MARTINELLI, GIOVANNI, Andrikovics, Hajnalka, Talmaci, R, Nomdedéu, J., Cross, N. C. P., S Akiki, Preudhomme, Claude, Ozbek, Ugur, Pajič, Tadej, Wang, L (Liang), Van Der Velden, Vincent H. J., Jansson, Mattias, Deprez, Liesbet +316 morecore +1 more sourcePhosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind +9 morewiley +1 more sourceThere is nothing minimal about residual disease [PDF]
Blood, 2018 Can the detection of measurable residual disease (MRD) become the standard approach for acute lymphoblastic leukemia (ALL)? In this issue of Blood,Wood et al1 use a highly sensitive sequencing approach that is an improvement on conventional methods by both performance characteristics and potential for standardization.openaire +2 more sources
