Results 71 to 80 of about 6,750 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Journal of Symbolic Logic, 2014 AbstractThis paper is devoted to o-minimalism, the study of the first-order properties of o-minimal structures. The main protagonists are the pseudo-o-minimal structures, that is to say, the models of the theory of all o-minimal L-structures, but we start with a more in-depth analysis of the well-known fragment DCTC (Definable Completeness/Type ...
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Digital Digital Minimalism: Paradigma Baru Pencegahaacn Adiksi Internet pada Generasi Z
Jurnal Ilmiah Bimbingan Konseling UndikshaPenggunaan internet yang berlebihan dapat mengganggu keseimbangan hidup, mempengaruhi kesehatan mental, dan mengurangi produktivitas. Oleh karena itu, penelitian ini bertujuan untuk mengeksplorasi penerapan digital minimalism sebagai solusi efektif ...
Fadillatul Nisa, Wahidah Fitriani
doaj +1 more source
Language, Thought, and Culture: Views and Arguments [PDF]
Taḥqīqāt-i Farhangī-i Īrān, 2009 This study follows two aims: one to review some late views on the relations among language, thought, and culture; and the other, to offer a new strategy, in a novel model, based on last achievements in the minimalist approach.
Keyvan Zahedi
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Administrative SciencesThis study investigates the impact of minimalism on ethical consumption within the framework of the Value–Identity–Personal Norms (VIP) model. Data were collected from 340 Turkish consumers using a convenience sampling method and an online survey ...
Müzeyyen Gelibolu, Kamel Mouloudj
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Minimalism, Technology and Electronic Music
, 2013 The adoption of both recording technology and electronically generated sounds has led to new explorations of ideas initially conceived for acoustic instruments, and has itself generated radically pioneering concepts.
Glover, Richard
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