Results 81 to 90 of about 11,183 (286)
Language, Thought, and Culture: Views and Arguments [PDF]
Taḥqīqāt-i Farhangī-i Īrān, 2009 This study follows two aims: one to review some late views on the relations among language, thought, and culture; and the other, to offer a new strategy, in a novel model, based on last achievements in the minimalist approach.
Keyvan Zahedi
doaj +1 more source
The Journal of Symbolic Logic, 2014 AbstractThis paper is devoted to o-minimalism, the study of the first-order properties of o-minimal structures. The main protagonists are the pseudo-o-minimal structures, that is to say, the models of the theory of all o-minimal L-structures, but we start with a more in-depth analysis of the well-known fragment DCTC (Definable Completeness/Type ...
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Administrative SciencesThis study investigates the impact of minimalism on ethical consumption within the framework of the Value–Identity–Personal Norms (VIP) model. Data were collected from 340 Turkish consumers using a convenience sampling method and an online survey ...
Müzeyyen Gelibolu, Kamel Mouloudj
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The effect of instructional design based on minimalism theory on learning and retention of students in higher education [PDF]
پژوهش در نظامهای آموزشی, 2020 The purpose of this study was to investigate the effect of the minimalism theory on learning and retention of learners in IT courses. Minimalist Theory consists of a basic framework that combines self-directed learning activities with technology, which ...
Ehsan Toofaninejad, Hashem Fardanesh
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The apparent simplicity of minimalism [PDF]
, 2002 The impetus for this design project involves the design methodology of minimalism. Minimalism is a term that is stated ubiquitously within the contemporary architectural context.
Hefley, David Ogden
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source