Results 91 to 100 of about 6,750 (303)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Problems With Minimalism

open access: yes, 2005
Much of Justice Sandra Day O'Connor's work on the Supreme Court embodies a commitment to judicial minimalism, understood as a preference for narrow rulings, closely attuned to particular facts.
Sunstein, Cass, Sunstein, Cass R.
core  

Konsep Diri Generasi Milenial Pelaku Minimalism Lifestyle

open access: yes, 2022
Advances This study aims to find out how the millennial generation's self-concept who applies Minimalism Lifestyle uses a communication perspective by looking at how the Millennial Generation of Minimalism Lifestyle actors communicate themselves ...
Azizah, Rahmalia Wulan
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Is Meaning Holism Compatible with Semantic Minimalism?

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.04 Meaning Holism and Contextualism are standardly acknowledged to be similar relativistic theories that often lead to similar troubles, in particular to issues concerning instability. On the other hand, the main
Filip Kawczyński
doaj  

Minimalism

open access: yes, 2019
Minimalism means living with intentionality. It is a mindset to remove the excesses of life and focus on what is truly important (Nicodemus 2015). Minimalism encourages people to let go of material goods that do not serve a purpose or bring joy to their ...
Ledder, Lindsay
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Stock

open access: yes, 2010
Includes bibliographical references.The practical component of this research takes the form of a sculptural interpretation of comprises a body of creative work supported by a theoretical discussion. This research is an observation and manifestation of my
Price, Catherine Jennifer
core  

Minimal R_1, minimal regular and minimal presober topologies

open access: yes, 2013
By means of filters, minimal R_1 and minimal regular topologies are characterized on suitable intervals consisting of non-trivial R_0 topologies.
Colasante, Maria Luisa   +1 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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