Results 111 to 120 of about 6,750 (303)

Minimalism in consumption

open access: yes, 2019
One of the trends in consumer behaviour that has been gradually gaining strength since the beginning of the 21st century is minimalism, also defined as anti-consumerism, voluntary simplicity and deconsumption.
Błoński, Krzysztof, Witek, Jolanta
core   +1 more source

Minimal charts

open access: yesTopology and its Applications, 2018
In this paper, we give definitions of three kinds of minimal charts, and we investigate properties of minimal charts and establish fundamental theorems characterizing minimal charts. To classify charts with two or three crossings we use the fundamental theorems. In the future paper, we give an numeration of the charts with two crossings.
Nagase, Teruo, Shima, Akiko
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Minimalism

open access: yes, 2000
A reappraisal of Minimalism from a contemporary perspective, this book documents the careers of its leading figures as well as the practices of other associated artists.
Smithson, Robert   +40 more
core  

Minimizing Breaks by Minimizing Odd Cycle Transversals

open access: yesIEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences
Constructing a suitable schedule for sports competitions is a crucial issue in sports scheduling. The round-robin tournament is a competition adopted in many professional sports. For most round-robin tournaments, it is considered undesirable that a team plays consecutive away or home matches; such an occurrence is called a break.
Koichi Fujii, Tomomi Matsui
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Living simply: embracing minimalism [PDF]

open access: yes
Minimalism appears as a ray of simplicity and peace in the middle of chaos in today's busy society. It promotes deliberate simplification in many facets of life to cultivate gratitude, satisfaction, and congruence with one's own ideals.
CEBOTARI, Daniela   +3 more
core  

Violation of minimalism

open access: yes, 2021
V této bakalářské práci je vytvořena dámská oděvní kolekce demonstrující narušení minimalismu. Výchozí materiál je obohacen transponováním jednoduchého malířsky vedeného vzoru do textilního vyjádření.
Márová, Nikola
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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