Results 101 to 110 of about 6,750 (303)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

1960s Fashion Minimalism

open access: yes, 2010
Fashion in London in the 1960s is often remembered as an exciting time of experimentation and bold choices, as well as the simple tailored lines of the mini skirt, A-line dress and trouser suit.
Finn, Angela L.
core  

Digital minimalism i ett hyperdigitalt samhälle [PDF]

open access: yes, 2022
Minimalism som filosofi och tillvägagångssätt i konsten har registrerat funnits sedan tidigt 1900-tal. Digital minimalism däremot är ett nytt fenomen, som belyser filosofin ur en synvinkel som främjar en individs välmående genom att minska på den ...
Mäenpää, Robin
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Julia Zhukova’s Porcelain Art: The Philosophy and Aesthetics of Minimalism [PDF]

open access: yesХудожественная культура
In the article, the researcher examines the conceptual and artistic features of the contemporary St. Petersburg porcelain artist Julia Zhukova’s works.
Shik Ida A.
doaj   +1 more source

The apparent simplicity of minimalism

open access: yes, 2002
The impetus for this design project involves the design methodology of minimalism. Minimalism is a term that is stated ubiquitously within the contemporary architectural context.
Hefley, David Ogden
core  

Transcription, Recording, and Authority in ‘Classic’ Minimalism

open access: yes, 2017
This article considers several prominent pieces of minimalism in their movement from primary sound recording to secondary transcription. In place of the score-based formalism of much musicological scholarship on minimalism, I draw on my own archival work
PATRICK NICKLESON
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

"Junction +4": A Foray into the Intersection of Minimalism and Indeterminacy

open access: yesAccelerando: BJMD, 2018
The main purpose of this article is to examine the methods and philosophies behind a work that the author composed for piano, “Junction +4.” The piece incorporates elements of both minimalism and indeterminacy.
Matthew Glenn Quick
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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