Results 101 to 110 of about 5,740,582 (295)

Partial regularity of almost minimizing rectifiable G chains in Hilbert space [PDF]

, 2019
We adapt to an infinite dimensional ambient space E.R. Reifenberg's epiperimetric inequality and a quantitative version of D. Preiss' second moments computations to establish that the set of regular points of an almost mass minimizing rectifiable G chain
De Pauw, Thierry, Züst, Roger
core   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

On low dimensional minimal sets [PDF]

Pacific Journal of Mathematics, 1972
Let (X, G, f) be a topological transformation group. Suppose that the phase space X is compact, separable metric, and locally contractible and the group G is the additive group of all real numbers R with the usual topology. If X is a minimal set of diπii (X) ^ 2 then X is a manifold, imposing a further condition on the action when dimz (X) = 2. Hence X
openaire   +3 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Multi-Objective Optimization for Determining Trade-Off between Output Power and Power Fluctuations in Wind Farm System

Energies, 2019
In this paper, a multi-objective optimization method is proposed to determine trade-off between conflicting operation objectives of wind farm (WF) systems, i.e., maximizing the output power and minimizing the output power fluctuation of the WF system.
Van-Hai Bui, Akhtar Hussain, Woon-Gyu Lee, Hak-Man Kim   +3 more
doaj   +1 more source

Minimization over Nonconvex Sets

Symmetry
Minimum norm problems consist of finding the distance of a closed subset of a normed space to the origin. Usually, the given closed subset is also asked to be convex, thus resulting in a convex minimum norm problem. There are plenty of techniques and algorithms to compute the distance of a closed convex set to the origin, which mostly exist in the ...
José Antonio Vilchez-Membrilla, Víctor Salas Moreno, Soledad Moreno-Pulido, Alberto Sánchez-Alzola, Clemente Cobos Sánchez, Francisco Javier García-Pacheco   +5 more
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The spectrum of minimal blocking sets

Discrete Mathematics, 1999
The authors show how minimal blocking sets can be obtained by modifying other ones. They introduce a combinatorial technique to prove the uniqueness of certain configurations realizing largest minimal blocking sets. They apply this to prove the nonexistence of a minimal blocking set of order 19 in \(\text{ PG}(2,7)\).
INNAMORATI, STEFANO, MATURO A.
openaire   +4 more sources