Results 91 to 100 of about 16,408 (292)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Minimum Aberration Blocking Schemes for Two-Level and Three-Level Fractional Factorial Designs [PDF]
, 2011 The concept of minimum aberration has been extended to choose blocked fractional factorial designs (FFDs). The minimum aberration criterion ranks blocked FFDs according to their treatment and block wordlength patterns, which are often obtained by ...
Hongquan Xu, Sovia Lau
core
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 The optimum balance values for different coefficient of spherical aberration (third and fifth degree also focal shift) were studied, the optical system includes different apertures (circle, ellipse, square and triangle) using point spread ...
Al. Badr Hassan +2 more
doaj
Higher order aberrations in a normal adult population
Journal of Current Ophthalmology, 2015 Purpose: To determine the distribution of Zernike coefficients and higher order aberrations in a normal population and its relationship with age, gender, biometric components, and spherical equivalent.
Hassan Hashemi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Minimum aberration two-level split-plot designs
, 1995 In this thesis a certain aspect of fractionated two-level split-plot designs is associated with a subset of the 2 \u27k fractional factorial designs.
Huang, Peng
core
A note on the connection between uniformity and generalized minimum aberration
, 2007 Primary 62K15, Secondary 62K05, Discrete discrepancy, factorial design, generalized minimum aberration, minimum projection variance, uniformity,
Qin, Hong +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Minimum Aberration Blocking Schemes for Two-Level and Three-Level Fractional Factorial Designs [PDF]
, 2004 The concept of minimum aberration has been extended to choose blocked fractional factorial designs (FFDs). The minimum aberration criterion ranks blocked FFDs according to their treatment and block wordlength patterns, which are often obtained by ...
Xu, Hongquan, Lau, Sovia
core