Results 91 to 100 of about 70,686 (289)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

An Aliasing Measure of Factor Effects in Three-Level Regular Designs

open access: yesEntropy
For three-level regular designs, the confounding from the perspectives of both factor and component effects leads to different results. The aliasing properties of factor effects are more significant than the latter in the experimental model.
Qiuying Chen, Zhiming Li, Zhi Li
doaj   +1 more source

Developments in Accommodating Intraocular Lenses

open access: yesTürk Oftalmoloji Dergisi, 2012
Technical progress in cataract surgery has decreased the incidence of severe complications in this type of surgery. The introduction of micro incision cataract surgery (MICS) (sub- 2.0 mm incision) allow the surgeon to achieve better postoperative ...
Zeki Tunç
doaj   +1 more source

Image processing based real-time variable-rate chemical spraying system for disease control in paddy crop

open access: yesArtificial Intelligence in Agriculture, 2020
The agrochemical application with conventional sprayers results in wastage of applied chemicals, which not only increases the economic losses but also pollutes the environment.
V.K. Tewari   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]

open access: yes, 2007
The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM   +5 more
core  

Effect of a Physical Phase Plate on Contrast Transfer in an Aberration-Corrected Transmission Electron Microscope

open access: yes, 2010
In this theoretical study we analyze contrast transfer of weak-phase objects in a transmission electron microscope, which is equipped with an aberration corrector (Cs-corrector) in the imaging lens system and a physical phase plate in the back focal ...
B. Gamm   +28 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Comparison of Optimum Balance Values For Different Coefficients of Spherical Aberration of Optical System Including Different Apertures

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
         The optimum balance values for different coefficient of spherical aberration (third and fifth degree also focal shift) were studied, the optical system includes different apertures (circle, ellipse, square and triangle) using point spread ...
Al. Badr Hassan   +2 more
doaj  

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