Results 81 to 90 of about 15,945 (255)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Clinical outcomes of the new generation VISUMAX 800 platform in small incision lenticule extraction for Myopia in Chinese patients

Scientific Reports
This retrospective multicentre study assessed early refractive outcomes and safety of small incision lenticule extraction (SMILE) in Chinese myopic eyes and characterised astigmatic accuracy and higher-order aberration (HOA) changes. Adults who underwent
Hui Zhang, Yuchen Mei, Quan Liu, Yawen Hao, Xuanyu Yang, Nian Guan, Xiaoli Li, Wentian Zhou   +7 more
doaj   +1 more source

Prediction of atmospheric environmental severity in Tibet based on polycarbonate (PC) aging behavior

工程科学学报
The spatiotemporal distribution of atmospheric environmental severity in Tibet was evaluated and predicted based on polycarbonate (PC) chromatic aberrations.
Dequan WU, Li QIN, Tiantian TAN, Xinghao CHEN, Fangchao ZHAO, Dawei ZHANG, Cuiwei DU   +6 more
doaj   +1 more source

Optical Design of the far Ultraviolet Imaging Spectrograph [PDF]

Journal of Astronomy and Space Sciences, 1998
We present the design specifications and the performance estimation of the FUVS (Far Ultraviolet Spectrograph) proposed for the observations of aurora, day/night airglow and astronomical objects on small satelltes in the spectral range of . The design of
K. S. Ryu, K. I. Seon, K. W. Min, J. Edelstein   +3 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

An algorithmic approach to finding factorial designs with generalized minimum aberration

Journal of Complexity, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fasheng Sun, Min-Qian Liu, Wenrui Hao
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Active Optics in Astronomy: Freeform Mirror for the MESSIER Telescope Proposal

Mathematical and Computational Applications, 2018
Active optics techniques in astronomy provide high imaging quality. This paper is dedicated to highly deformable active optics that can generate non-axisymmetric aspheric surfaces—or freeform surfaces—by use of a minimum number of actuators ...
Gerard Rene Lemaitre, Pascal Vola, Eduard Muslimov   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source