Results 81 to 90 of about 70,686 (289)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Zernike Polynomiales· for Opticl Ssytew. With Borizantal Recta_nguJar Aperture
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 For small aberrations, the ·suehl' ratio of an . im i'ng syStem • depends on trne aberration v·ariance. Its· aberration fu.nct1on ·is e:qJanded in terms 9f-l nike polynomials. which are_ oirrh6goilal over a circular apeltitte.
A, ,1J. AL-.llamdani, 8 Y. RAI-As di
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Designing the optimal Fresnel lenses by using Zemax software [PDF]
Journal of Optoelectronical Nanostructures, 2018 In this paper, the optimal Fresnel lenses are designed by Zemax software.The fundamental problem of the Fresnel lenses is the beam divergence, which wasresolved by decreeing the output stain diameter on the image plane.
Alireza Keshavarz +1 more
doaj
m-FISH analysis reveals complexity of chromosome aberrations in individuals occupationally exposed with internal plutonium: A pilot study to assess the relevance of complex aberrations as biomarkers of exposure to high-LET α particles [PDF]
, 2005 We recently demonstrated that a significant proportion of apparently stable insertions induced after exposure to a mean of 1 α particle/cell, detected using 3-colour FISH, were part of larger unstable complexes when visualised by 24-colour FISH ...
Anderson, RM +5 more
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
A Photolithography Process Design for 5 nm Logic Process Flow
Journal of Microelectronic Manufacturing, 2019 With the introduction of EUV lithography, the photolithographic process in 5 nm logic process can be simplified to use mostly single exposure method. In a typical 5 nm logic process, the contact-poly pitch (CPP) is 44-50 nm, the minimum metal pitch (MPP)
Qiang Wu +3 more
doaj +1 more source
Tomography-based definition of keratoconus for Down syndrome patients
Eye and Vision, 2020 Background To assess the diagnostic ability of Pentacam HR (Oculus Optikgeräte, GmbH, Wetzlar, Germany) tomographic indices in discriminating keratoconus (KC) and KC suspect (KCS) in 10- to 30-year-old patients with Down syndrome (DS).
Soheila Asgari +3 more
doaj +1 more source
Optimal Dark Hole Generation via Two Deformable Mirrors with Stroke Minimization
, 2011 The past decade has seen a significant growth in research targeted at space based observatories for imaging exo-solar planets. The challenge is in designing an imaging system for high-contrast.
Belikov, Ruslan +6 more
core +1 more source