Results 51 to 60 of about 15,300 (298)

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

(M, S)-OPTIMALITY CRITERION FOR REGULAR FRACTIONAL FACTORIAL DESIGNS

open access: yesPakistan Journal of Agriculture, Agricultural Engineering & Veterinary Sciences, 2014
The performance of (M, S)-optimality criterion on Regular two-level fractional factorial designs (FFD’s) is studied. The criterion has good estimation capacity and easy to compute.
M. H. Lakho   +3 more
doaj  

An easy to construct sub-micron resolution imaging system

open access: yesScientific Reports, 2020
We report an easy to construct imaging system that can resolve particles separated by $$\ge $$ ≥ 0.68 $$\upmu $$ μ m with minimum aberrations. Its first photon collecting lens is placed at a distance of 31.6 mm giving wide optical access.
Lakhi Sharma, A. Roy, S. Panja, S. De
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Evaluating Potential Ecological Risks of Heavy Metals of Textile Effluents and Soil Samples in Vicinity of Textile Industries

open access: yesSoil Systems, 2021
The present study pertains to assessing the heavy metal (Cd, Cr, Co, Cu, Pb, and Zn) contents of untreated and treated effluents of two textile industries and agricultural soil samples in the vicinity of these industries located in Ludhiana, Punjab ...
Jaskaran Kaur   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Error correction of a phase-only computer-generated hologram for an aspheric surface [PDF]

open access: yesJournal of the European Optical Society-Rapid Publications, 2014
When applying phase-only computer-generated hologram (CGH) as a standard model of optical measurement in computer-generated holography for aspheric surface testing, it has the advantage of simplifying optical path configuration and improving the ...
Zhang H.   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Bio-Inspired Wide-Angle Broad-Spectrum Cylindrical Lens Based on Reflections from Micro-Mirror Array on a Cylindrical Elastomeric Membrane

open access: yesMicromachines, 2014
We present a wide-angle, broad-spectrum cylindrical lens based on reflections from an array of three-dimensional, high-aspect-ratio micro-mirrors fabricated on a cylindrical elastomeric substrate, functionally inspired by natural reflecting superposition
Chi-Chieh Huang, Hongrui Jiang
doaj   +1 more source

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