Results 81 to 90 of about 1,942,479 (324)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Zernike Polynomiales· for Opticl Ssytew. With Borizantal Recta_nguJar Aperture

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
For  small   aberrations,  the  Â·suehl'  ratio of  an . im i'ng syStem • depends on trne aberration v·ariance. Its· aberration fu.nct1on ·is e:qJanded in terms 9f-l nike polynomials. which are_ oirrh6goilal over a circular apeltitte.
A, ,1J. AL-.llamdani, 8 Y. RAI-As di
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Designing the optimal Fresnel lenses by using Zemax software [PDF]

open access: yesJournal of Optoelectronical Nanostructures, 2018
In this paper, the optimal Fresnel lenses are designed by Zemax software.The fundamental problem of the Fresnel lenses is the beam divergence, which wasresolved by decreeing the output stain diameter on the image plane.
Alireza Keshavarz   +1 more
doaj  

A Photolithography Process Design for 5 nm Logic Process Flow

open access: yesJournal of Microelectronic Manufacturing, 2019
With the introduction of EUV lithography, the photolithographic process in 5 nm logic process can be simplified to use mostly single exposure method. In a typical 5 nm logic process, the contact-poly pitch (CPP) is 44-50 nm, the minimum metal pitch (MPP)
Qiang Wu   +3 more
doaj   +1 more source

Tomography-based definition of keratoconus for Down syndrome patients

open access: yesEye and Vision, 2020
Background To assess the diagnostic ability of Pentacam HR (Oculus Optikgeräte, GmbH, Wetzlar, Germany) tomographic indices in discriminating keratoconus (KC) and KC suspect (KCS) in 10- to 30-year-old patients with Down syndrome (DS).
Soheila Asgari   +3 more
doaj   +1 more source

Optimal Dark Hole Generation via Two Deformable Mirrors with Stroke Minimization

open access: yes, 2011
The past decade has seen a significant growth in research targeted at space based observatories for imaging exo-solar planets. The challenge is in designing an imaging system for high-contrast.
Belikov, Ruslan   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Developments in Accommodating Intraocular Lenses

open access: yesTürk Oftalmoloji Dergisi, 2012
Technical progress in cataract surgery has decreased the incidence of severe complications in this type of surgery. The introduction of micro incision cataract surgery (MICS) (sub- 2.0 mm incision) allow the surgeon to achieve better postoperative ...
Zeki Tunç
doaj   +1 more source

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