A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia +12 more
wiley +1 more source
Associations Between the Gut Microbiota and Physical Activity, Sedentary Behaviour and Physical Function in Community-Dwelling Older Adults. [PDF]
Ramos C +8 more
europepmc +1 more source
Sea cucumber mutable collagenous tissue (MCT) is a remarkable collagen‐based material which can rapidly undergo large changes in stiffness through transiently bound effector proteins. Here, we investigate the hierarchical structure and mechanical response of MCT from Cucumaria frondosa across length scales with a wide range of methods, also exploring ...
Nathalie R. H. Singh +7 more
wiley +1 more source
Charge Generation and Recombination Pathways in All‐Polymer Bulk Heterojunction Solar Cells
Multimodal spectroscopy and device analysis reveal how field‐dependent charge generation, transport limitations, and non‐geminate recombination govern performance losses in all polymer solar cells. The results identify the key processes controlling charge extraction and recombination, providing insights for the design of more efficient all‐polymer ...
Shahidul Alam +17 more
wiley +1 more source
Association of Osteosarcopenia with Functional Outcomes in Older Adult Patients Undergoing Rehabilitation. [PDF]
Mannen R, Maeda K, Inoue T, Shimizu A.
europepmc +1 more source
Two‐photon grayscale lithography (2GL) enables high‐speed and precise 3D printing of thermolyzed silica glass microstructures with optical‐grade surface quality, high quality factors, and mechanical strength utilizing a custom‐made pre‐glass resist based on polyhedral oligomeric silsesquioxane (POSS) modified with a high‐sensitivity Norrish type II ...
Jonathan L. G. Schneider +4 more
wiley +1 more source
Latin American Group for Maturity (GDLAM) protocol: a reliable method to assess the functional autonomy of community-dwelling older men. [PDF]
Huerta Ojeda Á +12 more
europepmc +1 more source
In this work, diamonds with negative charged silicon‐vacancy (SiV−) centers have been designed for use as thermometers in biomedical applications. Multiparametric analysis of the emission characteristics of the SiV− centers provides extraordinary sensitivity for temperature detection in the physiological temperature range.
María Gragera +6 more
wiley +1 more source
Effects of COgNitive Training in Community-dwelling Older Adults at High Risk for demENTia (CONTENT): study protocol of two double-blind, randomised, placebo-controlled trials. [PDF]
Pan Y +10 more
europepmc +1 more source
Volatile Relay Biosensing and Mobile Phone Imaging for Detection of Influenza Virus
Detection of volatile organic compounds is performed via a coupled enzymatic assay with mobile phone detection of the signal. Specific application demonstrated herein is the detection of influenza virus, across multiple levels of biological complexity, up to patient‐derived samples.
Dante G. Andersen +7 more
wiley +1 more source

