Results 91 to 100 of about 11,714 (256)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Association of Minimum Inhibitory Concentration Cluster Patterns with Dairy Management Practices for Environmental Bacteria Isolated from Bulk Tank Milk [PDF]

open access: bronze, 2005
John H. Kirk   +9 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Minimal Inhibitory Concentrations Of Azithromycin In Typhoidal Salmonella Isolated In Tertiary Care Setting

open access: yesPakistan Armed Forces Medical Journal
Objective: To determine the variations in minimal inhibitory concentrations (MIC) of Azithromycin amongst Salmonella typhi isolates. Study Design: Cross-sectional study.
Anam Tariq   +5 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Comparison of Disk Diffusion and E-Test with the Reference Method of Microbroth Dilution for Susceptibility Testing of Acinetobacter baumannii Isolates to Tetracyclines

open access: yesMedical Laboratory Journal, 2016
Background and Objective: Due to the continuous increase of multidrug-resistant Acinetobacter baumannii strains around the world, decision making for an effective treatment of infections caused by this organism depends on the results of antimicrobial ...
Abdollah Ardebili   +2 more
doaj  

Potential of diallyl sulfide from bulbs of Allium parvum to inhibit the growth and biofilm formation in Malassezia furfur MTCC 1374

open access: yesNotulae Scientia Biologicae
The bulbs of Allium parvum are used as a flavoring agent in diet and are conventionally assumed to treat skin infections. The current study evaluates the phytochemicals from organic extract of A.
Saravana P. KUMARI, E. MEIYAPPAN
doaj   +1 more source

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