Results 91 to 100 of about 439,248 (349)

The relationship between minimum inhibitory concentration and 28 day mortality in patients with a Gram-negative bloodstream infection: an analysis of data from a cohort study (BSI-FOO) [PDF]

, 2022
Rebecca Evans, Jessica Harris, Chris Rogers, Alasdair MacGowan   +3 more
openalex   +1 more source

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties [PDF]

, 2016
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position
Abdurrahman, Aktumsek, Adriano, Mollica, Bizzarri, Bruna, Chimenti, Paola, DE MONTE, Celeste, Emanuela, Mari, Gokhan, Zengin, Rivanera, Daniela, Secci, Daniela, Simone, Carradori, Zicari, Alessandra   +10 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Determination of Antimicrobial Activity of Various Extracts of Stinging Nettle (Urtica dioica)

Journal of Medicinal Plants, 2012
Background: Urtica dioica, or stinging nettle, is traditionally used in much frequency in northern Iran. A total of nine extracts were prepared using different organic solvents and by two extraction methods, either by using soxhlet extractor or ...
A Modarresi Chahardehi, D Ibrahim, S Fariza Sulaiman, F Aboulhassani   +3 more
doaj  

Efficacy of Different Obturating Materials - A Comparative Study

Indian Journal of Dental Research
Aim: To evaluate the efficacy of propolis and its combination products as an obturating material in comparison to Vitapex. Materials and Methods: Propolis collected from the primary source was extracted using organic solvents and laboratory bio-assayed ...
Shreya Gupta, Anil Gupta, Sumitra Arora, Ankit Srivastava   +3 more
doaj   +1 more source

Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) Assays Using Broth Microdilution Method v1

, 2023
The presented protocol outlines a comprehensive assessment of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values for bacterial cell cultures. These experiments are vital for screening bacterial susceptibility to antibiotics and substances with potential antibacterial properties.
Tomasz Swebocki, Alexandre Barras, Aleksandra Maria Kocot, magdalena.plotka not provided, rabah.boukherroub not provided   +4 more
openaire   +1 more source

In vitro control of plant pathogenic Xanthomonas spp. using Poncirus trifoliata Rafin [PDF]

, 2014
The secondary metabolites such as essential oil and pure compounds (limonin and imperatorin) from Poncirus trifoliata Rafin were tested for in vitro control of phytopathogenic bacteria of Xanthomonas spp.
Al-Reza, Sharif M., Islam, Rafiquel, Kang, Sun Chul, Rahman, Atiqur   +3 more
core  

Pharmacokinetic/pharmacodynamic integration and modelling of oxytetracycline for the porcine pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida [PDF]

, 2017
Pharmacokinetic–pharmacodynamic (PK/PD) integration and modelling were used to predict dosage schedules of oxytetracycline for two pig pneumonia pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida.
Aliabadi, Aliabadi, Blondeau, Brentnall, Brentnall, Cadwell, Dorey, Honeyman, Illambas, Illambas, Jong, Lees, Lees, Lees, Lees, Martinez, Mouton, Mouton, Nielsen, Nielsen, Nightingale, Nouws, Nouws, Nyberg, Papich, Potter, Rey, Sidhu, Sidhu, Toutain, Toutain, Toutain, Toutain, Vilalta, Yoshimura   +34 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Methicillin-Resistant Staphylococcus aureus and Vancomycin: Minimum Inhibitory Concentration Matters [PDF]

Clinical Infectious Diseases, 2012
These investigators found that elevated vancomycin MICs were associated with increased mortality in patients with MRSA infections, a result mostly driven by outcomes of bloodstream infections (BSIs). In contrast, excess mortality in association with elevated MICs was not seen in non-BSI MRSA infections.
openaire   +2 more sources