Results 81 to 90 of about 440,166 (303)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Determination of Antimicrobial Activity of Various Extracts of Stinging Nettle (Urtica dioica)

Journal of Medicinal Plants, 2012
Background: Urtica dioica, or stinging nettle, is traditionally used in much frequency in northern Iran. A total of nine extracts were prepared using different organic solvents and by two extraction methods, either by using soxhlet extractor or ...
A Modarresi Chahardehi, D Ibrahim, S Fariza Sulaiman, F Aboulhassani   +3 more
doaj  

PROFIL KROMATOGRAM DAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL RIMPANG BENGLE (Zingiber cassumunar Roxb.) TERHADAP BAKTERI ESCHERICHIA COLI IN VITRO [PDF]

, 2007
Background: Bengle (Zingiber cassumunar roxb.) was a plant which had been used by society since long time ago as a traditional herbal. It was predicted that there were anti-bacteria substances in bengle, so it might substitutes the utilization of ...
Raharjoyo, Lanjar
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Antimicrobial Effects of Ocimum gratissimum Extracts on the Spoilage Organisms Isolated from Yoghurt Samples

UMYU Journal of Microbiology Research
Ocimum gratissimum (OG) is recognised for its nutritional, antioxidant, and antimicrobial properties, making it a strong candidate for natural food preservation. This study evaluated the effects of ethanolic and aqueous OG leaf extracts against spoilage
Olawumi Amupitan Adefunke, Elizabeth Ajiboye Adeyinka, Rachael Adedayo Majekodunmi, Alex Amupitan Adewale   +3 more
doaj   +1 more source

Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) Assays Using Broth Microdilution Method v1

, 2023
The presented protocol outlines a comprehensive assessment of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values for bacterial cell cultures. These experiments are vital for screening bacterial susceptibility to antibiotics and substances with potential antibacterial properties.
Tomasz Swebocki, Alexandre Barras, Aleksandra Maria Kocot, magdalena.plotka not provided, rabah.boukherroub not provided   +4 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Efficacy of Different Obturating Materials - A Comparative Study

Indian Journal of Dental Research
Aim: To evaluate the efficacy of propolis and its combination products as an obturating material in comparison to Vitapex. Materials and Methods: Propolis collected from the primary source was extracted using organic solvents and laboratory bio-assayed ...
Shreya Gupta, Anil Gupta, Sumitra Arora, Ankit Srivastava   +3 more
doaj   +1 more source

Antibacterial Potential of Essential Oils Against Ground Beef Isolates

Revista Segurança Alimentar e Nutricional, 2017
The objective of this study was to evaluate the antibacterial activity of different EOs against Escherichia coli, Salmonella spp., and coagulase-positive staphylococcus isolated from ground beef. The EOs had values varying from 0.78μl/mL to 100μl/mL, and
Lisiane Martins Volcão, Juliana de Lima Marques, Lucas Moreira dos Santos, Suzane Olachea Allend, Kamila da Cunha Furtado, Rosana Serpa, Gladis Aver Ribeiro   +6 more
doaj   +1 more source

PENENTUAN KONSENTRASI HAMBAT MINIMUM DAN KONSENTRASI BUNUH MINIMUM MINYAK ATSIRI KULIT JERUK NIPIS (CITRUS AURANTIFOLIA (CHRISTM.) SWINGLE) TERHADAP ISOLAT KLINIS CANDIDA ALBICANS [PDF]

, 2015
Candida albicans adalah salah satu jamur penyebab infeksi oportunistik pada manusia. Saat ini telah dilaporkan adanya resistensi Candida albicans terhadap beberapa golongan obat antijamur sehingga perlu dilakukan pencarian dan pengembangan obat antijamur
Fauzi Satria
core