Results 51 to 60 of about 2,710,081 (306)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2008 We study whether finite temperature corrections decompactify the internal space in KKLT compactifications with an uplifting sector given by a system that exhibits metastable dynamical supersymmetry breaking.
Abe +63 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Minimum Ignition Temperature of Hybrid Mixtures
Chemical Engineering Transactions, 2022 Although the minimum ignition temperature is an important safety characteristic and hybrid mixtures are of high relevance in different industrial processes, the focus of research is directed towards single-substance systems.
Dieter Gabel +3 more
doaj +1 more source
Universal Minimum Heat Leak on Low-Temperature Metallic Electrical Leads
, 2006 Low-temperature electronic systems require electrical leads which have low electrical resistance to provide bias current I without excessive voltage drop V. But proper cryogenic design also requires high thermal resistance to maintain a minimum heat leak
Kadin, Alan M.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2005 We present a 3-D NLTE Monte Carlo radiative transfer code that we use to study the temperature and ionization structure of Keplerian disks around Classical Be stars.
Bjorkman, J. E., Carciofi, A. C.
core +1 more source
Observation of a temperature dependent electrical resistance minimum above the magnetic ordering temperature in Gd$_2$PdSi$_3$ [PDF]
, 1998 Results on electrical resistivity, magnetoresistance, magnetic Results on electrical resistivity, magnetoresistance, magnetic susceptibility, heat capacity and Gd Mossbauer measurements on a Gd-based intermetallic compound, Gd$_{2}$PdSi$_{3}$ are ...
+9 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source