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Fermented Red Ginseng Restores Age-Associated Insulin Homeostasis and Gut Microbiome Balance in Mice. [PDF]

open access: yesBiology (Basel)
Lee DY   +7 more
europepmc   +1 more source
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Increasing minor ginsenosides contents and enhancing neuroprotective effects of total ginsenosides fermented by Lactiplantibacillus plantarum

Fitoterapia, 2023
Minor ginsenosides have been proven to have higher pharmacological activity than the major ginsenosides. The transformation of major ginsenosides to minor ginsenosides by lactic acid bacteria was considered to be a promising method. Therefore, this study focuses on utilizing glycosidase-producing Lactiplantibacillus plantarum GLP40 to transform total ...
Ge, Yang   +6 more
openaire   +2 more sources

Characterization of the ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum and bioconversion of major ginsenosides into minor ginsenosides

Applied Microbiology and Biotechnology, 2012
This study focused on the cloning, expression, and characterization of ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum KACC 20028(T) in order to biotransform ginsenosides efficiently. The gene, termed as bglAm, encoding a β-glucosidase (BglAm) belonging to the glycoside hydrolase family 3 was cloned. bglAm consisted of 1,830
Cui, CH Cui, Chang-Hao   +2 more
openaire   +3 more sources

Synthesis of ginsenoside Rg3, a minor constituent of Ginseng Radix

Carbohydrate Research, 1997
Glycosylation of 12beta-acetoxy-dammar-24-en-3beta,20(S)-diol (4), with hepta-O-acetyl-alpha-sophorosyl bromide (5) under catalysis by Ag2CO3 or Ag2O afforded a chromatographically unseparated mixture of the alpha- and beta-linked octaacetates 6 and 7 in an approximately 2.5:1 ratio. After deprotection and chromatographic purification, the free alpha- (
V P, Anufriev   +6 more
openaire   +2 more sources

A literature update elucidating production of Panax ginsenosides with a special focus on strategies enriching the anti-neoplastic minor ginsenosides in ginseng preparations

Applied Microbiology and Biotechnology, 2017
Ginseng, an oriental gift to the world of healthcare and preventive medicine, is among the top ten medicinal herbs globally. The constitutive triterpene saponins, ginsenosides, or panaxosides are attributed to ginseng's miraculous efficacy towards anti-aging, rejuvenating, and immune-potentiating benefits.
Archana Mathur   +2 more
exaly   +3 more sources

Preparation of minor ginsenosides C-K and C-Mx from protopanaxadiol ginsenosides of American ginseng leaves by a enzyme from Aspergillus sp.agl-84 strain

Process Biochemistry, 2021
Abstract To improve utilization of American-ginseng-leaf ginsenosides, the PPD-ginsenosides from American-ginseng-leaves was reacted by a ginsenosidase type-I from Aspergillus sp.agl-84 to prepare minor ginsenosides C-K and C-Mx. PPD-ginsenosides, containing over 79 % of Rb3 and Rd, were separated from American-ginseng-leaves; the yield was 10.5 ...
Hongshan Yu, Chunying Liu
exaly   +2 more sources

Enhanced biotransformation of the minor ginsenosides in red ginseng extract by Penicillium decumbens β-glucosidase

Enzyme and Microbial Technology, 2022
Compound K (C-K) and Rh2, which are present at low levels in ginseng and ginseng extracts, have higher intestinal absorption rates than other ginsenosides. Here, we attempted to convert ginsenoside Rb1 to C-K using a β-glucosidase from Penicillium decumbens.
So-Yeon, Kim   +7 more
openaire   +2 more sources

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