Results 61 to 70 of about 737,744 (287)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Jiaoshi jiaoyu xuebaoAs a comprehensive education and livelihood project, the construction of the rural teacher workforce is an important aspect of promoting the strategy of rural revitalization and deepening educational reform.
CHEN Hui, LI Chencheng
doaj +1 more source
Transnationalization of human rights norms and its impact on internally displaced Kurds [PDF]
, 2005 This paper addresses the less researched topic of internal displacement as a human rights issue and analyzes the extent that the transnationalization of human rights issues and the pressures from regional organizations affected the rights of ethnic ...
Celik, Ayse Betul, Çelik, Ayşe Betül
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Ethnic minority immigrants and their children in Britain [PDF]
This paper investigates educational attainment and economic behaviour of ethnic minority immigrants and their children in Britain. Despite their strong educational achievements, ethnic minority immigrants and their descendants exhibit lower employment ...
Christian Dustmann +1 more
core +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Eminent Domain and Racial Discrimination: A Bogus Equation [PDF]
, 2011 This paper is a transcript of testimony by Professor J. Peter Byrne before the U.S. Civil Rights Commission on August 12, 2011. This hearing addresses claims that the use of eminent domain for economic development unfairly and disproportionately harms ...
Byrne, J. Peter
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Humanities & Social Sciences CommunicationsThis study explores the association of secondary vocational education (SVE) on subjective class identification in China, focusing on comparisons with compulsory and academic high school education, and analyzing regional and historical variations.
Penghui Wu, Ming Zhang, Demei Yang
doaj +1 more source