Results 71 to 80 of about 939,818 (306)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Minority Veto Rights in Kosovo’s Democracy

open access: yesAge of Human Rights Journal, 2019
The political system of Kosovo belongs to the power sharing democracies. Indeed, it has all the characteristics of Consociational Democracy. In addition to that, minority veto rights are absolute and go above the aims of this type of democracy. As it is
Behar Selimi
doaj   +2 more sources

Individual and Group Rights of Liberal Multiculturalism

open access: yesMigracijske i etničke teme, 2010
The paper discusses the implementation of minority members’ protection through political and civil rights. In the debates on minority members’ rights, the issue is whether the very individual rights of traditional liberalism are sufficient for minority ...
Vesna Stanković Pejnović
doaj  

Hungarian-Slovak “Cold War” and the Question Of “Hungarians Abroad” in Hungary-Slovakia Relations [PDF]

open access: yesRomanian Journal of European Affairs, 2009
The question of EU relations with countries of Central and Eastern Europe (CEE) has been widely researched and debated both in political circles and the academia, especially in the light of the EU accession.
Galina Nelaeva
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Promovarea eficientă a Declarației ONU cu privire la drepturile persoanelor aparținând minorităților naționale sau etnice, religioase și lingvistice - Raport al Raportorului Special al ONU privind problemele minorităților (ONU, 2020) [PDF]

open access: yesDrepturile Omului, 2020
In the analyzed report, the Special Rapporteur on minority issues, Fernand de Varennes, briefly presents his activities in 2019 and 2020 to the General Assembly, highlighting the continuous work on the thematic priorities of statelessness, education and ...
Adina – Maria Nikolić
doaj  

PROTECTION OF NATIONAL MINORITIES IN ROMANIA AND REPUBLIC OF MOLDOVA. GUIDELINES [PDF]

open access: yes
In light of recent conflicts on the issue of minorities and European regulations, the issue of the protection of minority rights appears to be increasingly more important in a world of multiculturalism, which should be a world of dialogue and respect of ...
Roxana Alina Petraru
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Supreme Court As Risk Manager: An Analysis of Skinner [PDF]

open access: yes, 1992
Examining a recent case in which the U.S. Supreme Court approved the collection of blood and urine samples from railroad employees, the authors conclude that, in attempting to improve railroad safety, both majority and minority opinions reflected undue ...
Mogan, James F.   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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