Results 201 to 210 of about 54,811 (219)
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Rheumatology
Abstract Objective This study examines how exosomal miR-132-3p from M1 macrophages contributes to the development of systemic lupus erythematosus (SLE)-associated DAH and the molecular mechanisms involved.
Xun Chen +5 more
semanticscholar +2 more sources
Abstract Objective This study examines how exosomal miR-132-3p from M1 macrophages contributes to the development of systemic lupus erythematosus (SLE)-associated DAH and the molecular mechanisms involved.
Xun Chen +5 more
semanticscholar +2 more sources
MiR-132-3p serves as a tumor suppressor in mantle cell lymphoma via directly targeting SOX11
Naunyn-Schmiedeberg's Archives of Pharmacology, 2020Mantle cell lymphoma (MCL) is an uncommon type of non-Hodgkin's lymphoma (NHL), comprising about 6% of NHL cases. SOX11 is a member of the group C of Sry-related high-mobility group (HMG) box (Sox) transcription factors, which is ubiquitously expressed in approximate 90% MCL cases.
Baoyu, Wu +4 more
openaire +2 more sources
ACS Biomaterials Science & Engineering, 2021
Titanium and its alloys have been widely used as bone implants, but for reduced treatment span, improvements are urgently needed to achieve faster and better osteointegration. In this study, we found that miR-132-3p inhibited bone-marrow-derived stem cell (BMSC) osteogenic differentiation via targeting BMP2, and that inhibiting miR-132-3p could ...
Yiming Li +8 more
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Titanium and its alloys have been widely used as bone implants, but for reduced treatment span, improvements are urgently needed to achieve faster and better osteointegration. In this study, we found that miR-132-3p inhibited bone-marrow-derived stem cell (BMSC) osteogenic differentiation via targeting BMP2, and that inhibiting miR-132-3p could ...
Yiming Li +8 more
openaire +2 more sources
Revista Espanola de Enfermedades Digestivas
BACKGROUND Previous studies have demonstrated that PNI can predict the prognosis of gastric cancer (GC) patients. However, few studies have focused on the auxiliary role of miRNA in predicting the prognosis of GC.
Jing Qin +5 more
semanticscholar +1 more source
BACKGROUND Previous studies have demonstrated that PNI can predict the prognosis of gastric cancer (GC) patients. However, few studies have focused on the auxiliary role of miRNA in predicting the prognosis of GC.
Jing Qin +5 more
semanticscholar +1 more source
Genetic Testing and Molecular Biomarkers, 2021
Introduction: Brain-derived neurotrophic factor (BDNF) levels are reduced in advanced stages of multiple sclerosis (MS) and may be associated with reduced regenerative capability in progressive MS.
F. Sağır +7 more
semanticscholar +1 more source
Introduction: Brain-derived neurotrophic factor (BDNF) levels are reduced in advanced stages of multiple sclerosis (MS) and may be associated with reduced regenerative capability in progressive MS.
F. Sağır +7 more
semanticscholar +1 more source
The FASEB Journal, 2022
Mesial temporal lobe epilepsy (MTLE) is one of the most common refractory epilepsies and is usually accompanied by a range of brain pathological changes, such as neuronal injury and astrocytosis.
Wen Zhang +7 more
semanticscholar +1 more source
Mesial temporal lobe epilepsy (MTLE) is one of the most common refractory epilepsies and is usually accompanied by a range of brain pathological changes, such as neuronal injury and astrocytosis.
Wen Zhang +7 more
semanticscholar +1 more source
Molecular Pharmaceutics
Chronic diabetic wounds represent a significant clinical challenge because of impaired healing processes, which require innovative therapeutic strategies.
Liming Zheng +5 more
semanticscholar +1 more source
Chronic diabetic wounds represent a significant clinical challenge because of impaired healing processes, which require innovative therapeutic strategies.
Liming Zheng +5 more
semanticscholar +1 more source
Cell Cycle
Exosomes secreted by mesenchymal stem cells (MSCs) have been considered as a novel biological therapy for myocardial ischemia/reperfusion injury (MIRI). However, the underlying mechanism of exosomes has not been completely established, especially in the ...
Hongkun Wu +11 more
semanticscholar +1 more source
Exosomes secreted by mesenchymal stem cells (MSCs) have been considered as a novel biological therapy for myocardial ischemia/reperfusion injury (MIRI). However, the underlying mechanism of exosomes has not been completely established, especially in the ...
Hongkun Wu +11 more
semanticscholar +1 more source
Journal of Cellular Biochemistry, 2017
AbstractPrevious study showed that miRNA aberrant expression is involved in chondrogenic differentiation. In this study, we aimed to investigate the effects of miR‐132‐3p on chondrogenic differentiation and the underlying mechanisms. First, quantitative PCR were performed to determine the level of MiR‐132‐3p.
Xiaozhong Zhou +8 more
openaire +2 more sources
AbstractPrevious study showed that miRNA aberrant expression is involved in chondrogenic differentiation. In this study, we aimed to investigate the effects of miR‐132‐3p on chondrogenic differentiation and the underlying mechanisms. First, quantitative PCR were performed to determine the level of MiR‐132‐3p.
Xiaozhong Zhou +8 more
openaire +2 more sources
Downregulation of GSK3B by miR-132-3p Enhances Etoposide-Induced Breast Cancer Cell Apoptosis.
Annals of clinical and laboratory science, 2021MicroRNAs (miRNAs) have been confirmed to play an essential role in modulating cancer cell proliferation, metastasis, and sensitivity to chemotherapy. However, the correlation between miR-132-3p expression and etoposide (VP16) induced apoptosis in human breast cancer cells remains poorly understood.Six datasets, including three gene expression profile ...
Chengshan, Xu +3 more
openaire +1 more source